J Korean Ophthalmol Soc > Volume 60(7); 2019 > Article
Journal of the Korean Ophthalmological Society 2019;60(7):676-684.
DOI: https://doi.org/10.3341/jkos.2019.60.7.676    Published online July 15, 2019.
Interocular Symmetry of Optical Coherence Tomography Angiography Parameters in Normal Eyes of Korean Adults.
Hye Jin Park, Hyung Bin Lim, Min Woo Lee, Young Joon Jo, Jung Yeul Kim
1Department of Ophthalmology, Chungnam National University Hospital, Daejeon, Korea. kimjy@cnu.ac.kr
2Department of Ophthalmology, Armed Forces Capital Hospital, Seongnam, Korea.
한국 성인의 정상안에서 빛간섭단층혈관조영술 측정치의 양안 대칭성
박혜진1⋅임형빈1,2⋅이민우1⋅조영준1⋅김정열1
충남대학교 의과대학 안과학교실1, 국군수도병원 안과2
Correspondence:  Jung Yeul Kim,
Email: kimjy@cnu.ac.kr
Received: 20 December 2018   • Revised: 18 February 2019   • Accepted: 19 June 2019
Abstract
PURPOSE
To evaluate the interocular symmetry of microvascular parameters measured by optical coherence tomography angiography (OCTA) in normal eyes of Korean adults. METHODS: We retrospectively reviewed the retinal microvascular structure of 91 healthy Korean subjects (182 eyes). We used OCTA to measure the area of the foveal avascular zone (FAZ), vessel density (VD), and perfusion density (PD) in both eyes. Intraclass correlation coefficients (ICCs), coefficients of variation (CVs), and Pearson correlation coefficients were calculated to evaluate the extent of agreement and correlations between binocular OCTA measurements. RESULTS: Both eyes had similar microvascular characteristics: FAZ area (right eye: 0.31 ± 0.11 mm², left eye: 0.30 ± 0.10 mm², p = 0.98), FAZ perimeter (right eye: 2.35 ± 0.45 mm, left eye: 2.36 ± 0.39 mm, p = 0.86). VD 1-mm center (right eye: 9.42 ± 2.75, left eye: 9.14 ± 2.96, p = 0.163), full area (right eye: 19.94 ± 1.65, left eye: 19.72 ± 1.76, p = 0.285), and PD 1-mm center (right eye: 0.16 ± 0.05, left eye: 0.16 ± 0.05, p = 0.151), full area (right eye: 0.36 ± 0.03, left eye: 0.36 ± 0.04, p = 0.716). All ICC values were above 0.8 and all CVs below 10%. CONCLUSIONS: The microvascular structure, as represented by the VD, PD, and FAZ area measured via OCTA, was bilaterally symmetric in normal eyes of Korean adults.
Key Words: Foveal avascular zone;Interocular symmetry;Microvascular parameters;Optical coherence tomography angiography


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