J Korean Ophthalmol Soc > Volume 60(12); 2019 > Article
Journal of the Korean Ophthalmological Society 2019;60(12):1155-1161.
DOI: https://doi.org/10.3341/jkos.2019.60.12.1155    Published online December 15, 2019.
Clinical Analysis of Findings for Anterior Segment Optical Coherent Tomography in Recurrent Corneal Erosion Syndrome.
Yu Min Kim, Hee Dong Eom, Dong Hee Yoon, Hong Kyun Kim
Department of Ophthalmology, School of Medicine, Kyungpook National University, Daegu, Korea. okeye@knu.ac.kr
반복각막진무름에서 전안부빛간섭단층촬영으로 관찰되는 비정상 소견에 대한 임상분석
김유민 · 엄희동 · 윤동희 · 김홍균
경북대학교 의과대학 안과학교실
Correspondence:  Hong Kyun Kim,
Email: okeye@knu.ac.kr
Abstract
PURPOSE
To evaluate the correlation between abnormal findings seen in anterior segment optical coherent tomography and the recurrence rate in patients with recurrent corneal erosion syndrome. METHODS: Between January 2015 and August 2018, 53 eyes of 52 patients who had been diagnosed with recurrent corneal erosion syndrome were included in the study. Follow-up was performed for 12 months. To confirm the recurrence, we questioned the subjects on their symptoms and performed slit lamp examinations. At the first visit, the second week, and the first month, we performed anterior segment optical coherent tomography to identify pathologic findings for recurrent corneal erosion syndrome. RESULTS: In 12 months, 29 eyes (54.7%) had a recurrence of corneal erosion and 24 eyes (45.3%) had no recurrence. There was no significant difference in age, sex, trauma, diabetes mellitus, or meibomian gland dysfunction between the recurrent and non-recurrent groups. Among the anterior segment optical coherent tomography findings, anterior stromal hyper-reflectivity, undetected epithelial basement membrane, intraepithelial basement membrane, intraepithelial inclusions were not significantly different between the two groups. In the first month, corneal epithelial edema was 82.8% in the recurrent group, but 33.3% in the non-recurrent group. It was significantly different (p = 0.000). Corneal epithelial thickness lowered significantly in the non-recurrent group, but not in the recurrent group in the first month. In other words, epithelial edema improved in the non-recurrent group, whereas epithelial edema did not improve in the recurrent group. CONCLUSIONS: If corneal epithelial edema is not treated in patients with recurrent corneal erosion syndrome, high possibility of a recurrence should be considered.
Key Words: Corneal edema;Corneal epithelial edema;Corneal epithelial thickness;Corneal epithelium;Recurrent corneal erosion


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