J Korean Ophthalmol Soc > Volume 61(1); 2020 > Article
Journal of the Korean Ophthalmological Society 2020;61(1):1-8.
DOI: https://doi.org/10.3341/jkos.2020.61.1.1    Published online January 15, 2020.
Clinical Aspects of Phlyctenular Keratoconjunctivitis Using a Tear Film Interferometer.
Dong Hyun Kang, Sang Wroul Song, Byung Yeop Kim, Kyu Yeon Hwang, Kook Young Kim
Myung-Gok Eye Research Institute, Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea. m_d@daum.net
플릭텐각결막염환자의 눈물간섭계를 이용한 임상양상 분석
강동현 · 송상률 · 김병엽 · 황규연 · 김국영
건양대학교 의과대학 김안과병원 안과학교실 명곡안연구소
Correspondence:  Kook Young Kim,
Email: m_d@daum.net
Received: 19 July 2019   • Revised: 16 August 2019   • Accepted: 30 December 2019
To evaluate clinical findings in phlyctenular keratoconjunctivitis patients and assess the function and morphology of Meibomian glands using an interferometer (LipiView®, TearScience, Morrisville, NC, USA) in such patients. METHODS: This retrospective study included 19 eyes of 13 patients diagnosed with phlyctenular keratoconjunctivitis. The lipid layer thickness (LLT) and meibograph of each eye was quantified by tear interferometry. Tear film break-up time (TBUT) and corneal staining score were measured. Meibomian gland morphology (lid margin vascularity, plugging of gland orifices, lid margin irregularity, lid margin thickening, and partial glands) was evaluated based on anterior photographs and meibographs. RESULTS: The mean age was 21.3 years (8–44 years). Mean BUT and Oxford corneal staining scores were 2.6 ± 1.2 seconds and 1.9 ± 0.8, respectively. Abnormal findings of the Meibomian glands were observed in all patients. The mean LLT was 79.6 ± 27.4 µm and the incomplete eye blinking frequency was 3.8 ± 5.9 during 20 seconds. The graphs of the tear lipid layer showed various patterns such as flat, up-hill, down-hill, and mixed. CONCLUSIONS: Meibomian gland dysfunctions and changes in the tear film lipid layer were noted in patients with phlyctenular keratoconjunctivitis. These factors are to be considered for the treatment of phlyctenular keratoconjunctivitis in young patients under 10 years of age.
Key Words: Dry eye;Lipid layer thickness;Meibomian gland;Phlyctenular keratitis;Tear film stability

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