J Korean Ophthalmol Soc > Volume 56(11); 2015 > Article
Journal of the Korean Ophthalmological Society 2015;56(11):1767-1776.
DOI: https://doi.org/10.3341/jkos.2015.56.11.1767    Published online November 15, 2015.
Thickness in Ganglion Cell-Inner Plexiform Layer on Spectral-Domain Optical Coherence Tomography after Cataract Surgery.
Woo Beom Shin, Hyun Kyo Jeong, Ji Hyun Kim, Jun Mo Lee, Sa Min Hong, Chan Yun Kim, Gong Je Seong, Kyoung Soo Park
1Siloam Eye Hospital, Seoul, Korea. march789@siloam.co.kr
2Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
백내장 수술 후 스펙트럼영역 빛간섭단층촬영에서 나타나는 신경절세포-내망상층 두께 변화
신우범1⋅정현교1⋅김지현1⋅이준모1⋅홍사민2⋅김찬윤2⋅성공제2⋅박경수1
실로암안과병원1, 연세대학교 의과대학 안과학교실2
Received: 27 March 2015   • Revised: 29 June 2015   • Accepted: 21 August 2015
Abstract
PURPOSE
To assess changes in ganglion cell-inner plexiform layer (GCIPL) thickness after cataract surgery using spectral-domain optical coherence tomography (OCT). METHODS: Forty-three eyes of 33 patients, who underwent cataract surgery were imaged with spectral-domain OCT before and after surgery to measure peripapillary retinal nerve fiber layer (RNFL) and GCIPL thickness, signal strength (SS), quadrant, 12 clock-hour RNFL thickness and sectoral GCIPL thickness. RESULTS: The postoperative SS, RNFL and GCIPL thickness were higher than before surgery (p < 0.05). Multivariate analysis showed that endothelial cell count and preoperative SS were significantly correlated with SS changes in RNFL parameters and preoperative SS was significantly correlated with SS changes in GCIPL parameters. Univariate analysis indicated that age was significantly correlated with RNFL thickness changes in RNFL parameters and no factor was correlated with GCIPL thickness in GCIPL parameters (p < 0.05). CONCLUSIONS: Cataracts may decrease peripapillary RNFL and GCIPL thickness measurements and SS on OCT scans. Peripapillary RNFL and GCIPL thickness measurements should be interpreted with caution in eyes with significant cataracts.
Key Words: Cataract surgery;Ganglion cell-inner plexiform layer;Optical coherence tomography;Peripapillary retinal nerve fiber layer


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