J Korean Ophthalmol Soc > Volume 56(11); 2015 > Article
Journal of the Korean Ophthalmological Society 2015;56(11):1804-1809.
DOI: https://doi.org/10.3341/jkos.2015.56.11.1804    Published online November 15, 2015.
Macular Infarction Following Intravitreal Triamcinolone Injection for Treatment of Central Retinal Vein Occlusion.
Jae Hoon Lee, Tai Kyong Kim, Young Chun Lee, Mee Yon Lee
Department of Ophthalmology and Visual Science, The Catholic University of Korea Uijeongbu St. Mary's Hospital, The Catholic University of Korea School of Medicine, Uijeongbu, Korea. deenie@hanmail.net
중심망막정맥폐쇄 환자에서 유리체강내 트리암시놀론 주입술 후 발생한 황반허혈 1예
이재훈⋅김태경⋅이영춘⋅이미연
가톨릭대학교 의과대학 가톨릭대학교 의정부성모병원 안과 및 시과학교실
Received: 15 May 2015   • Revised: 17 June 2015   • Accepted: 14 August 2015
Abstract
PURPOSE
To report a case of macular infarction following intravitreal triamcinolone injection for treatment of central retinal vein occlusion. CASE SUMMARY: A 75-year-old male visited our clinic for visual disturbance in his left eye and was diagnosed with macular infarction in his right eye. His medical history included type 2 diabetes, alcoholic liver cirrhosis, and hepatocellular carcinoma. After fundus examination, the patient was diagnosed with central vein occlusion with macular edema and intravitreal triamcinolone was administered to reduce edema. Within 1 week of treatment with the intravitreal injection, the patient experienced a significant decrease in visual acuity. Fluorescein angiogram showed an enlargement of the foveal avasacular zone, although optical coherence tomography (OCT) showed a decreased macular edema. Despite normalization of macular thickness on OCT and cessation of leakage on angiography, visual acuity remained at the same level during 2 months of follow-up. CONCLUSIONS: Intravitreal anti-vascular endothelial growth factor injection as well as intravitreal triamcinolone injection can cause macular ischemia which should be considered with the adopted treatment regimen for patients with ischemic risk factors.
Key Words: Central retinal vein occlusion;Ischemic maculopathy;Triamcinolone acetonide


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