Influence of Intravitreal Bevacizumab Injection on Formation of Collateral Vessels in Branch Retinal Vein Occlusion. |
Yeng Woo Son, Seung Woo Lee |
Department of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea. jazzhanul@hanmail.net |
망막분지정맥폐쇄에서 유리체강 내 베바시주맙 치료가 측부혈관 형성에 미치는 영향 |
손영우⋅이승우 |
동국대학교 의과대학 안과학교실 |
Correspondence:
Seung Woo Lee |
Received: 27 February 2015 • Revised: 17 June 2015 • Accepted: 25 January 2016 |
Abstract |
PURPOSE To evaluate the influence of retinal collateral vessels in eyes with macular edema secondary to branch retinal vein occlusion (BRVO) treated with intravitreal bevacizumab (IVB). METHODS: We reviewed the medical records of patients with BRVO who were followed up for 12 months. To compare formations of collateral vessels, the patients were divided into 2 groups. The treatment group included 20 patients (20 eyes) treated with IVB, and the control group included 41 patients (41 eyes) without treatment. RESULTS: In the treatment group, the mean age was 58.4 ± 9.5 years. The average number of IVB injections performed during the 12 months was 4.5 ± 2.5 (range 2 to 8). After 12 months from diagnosis, 13 eyes (65%) presented with collateral vessels. In the control group, the mean age was 60.6 ± 9.3 years and 28 eyes (68.3%) presented with collateral vessel after 12 months. There was no difference in incidence of collateral vessel formation between the treatment group and the control group (p = 0.574). CONCLUSIONS: IVB does not influence the formation of retinal collateralization in eyes treated for macular edema secondary to BRVO. |
Key Words:
Bevacizumab;Collateral Vessels;Macular Edema;Retinal Vein Occlusion |