J Korean Ophthalmol Soc > Volume 57(5); 2016 > Article
Journal of the Korean Ophthalmological Society 2016;57(5):843-846.
DOI: https://doi.org/10.3341/jkos.2016.57.5.843    Published online May 15, 2016.
Case of Acute Myeloid Leukemia with Mass of Eyelid and Conjunctiva in the Early Stage.
Dong Ju Kim, Min Wook Chang
Department of Ophthalmology, Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea. mdjacob@naver.com
눈꺼풀 및 결막 종양으로 처음 발현된 급성 골수성 백혈병
김동주⋅장민욱
동국대학교 의과대학 일산병원 안과학교실
Received: 28 January 2016   • Revised: 9 March 2016   • Accepted: 6 April 2016
Abstract
PURPOSE
To report a case of an 82-year-old male with acute myeloid leukemia presenting with bilateral isolated conjunctival and eyelid masses. CASE SUMMARY: An 82-year-old male presented with a bilateral conjunctival mass and right eyelid mass occurring 10 days prior. He was diagnosed with prostate cancer 8 years ago and complete recovery was achieved using selective mass chemotherapy. He experienced a stroke 4 years ago and was treated using a carotid artery stent insertion and medication. In the initial laboratory test, hemoglobin was 13.7 g/dL and leukocyte count 5,530/mm3(neutrophil 74.4%, lymphocyte 10%, monocyte 11.8%). Light reflex, movement of extraocular muscle and fundus examination were all normal. Biopsy was performed 1 week after the first visit. Seven days after biopsy, he complained of sudden dyspnea and febrile sense and was admitted to the intensive care unit via the emergency room (ER). The laboratory tests performed in the ER showed hemoglobin was 9.6 g/dL and leukocyte count was 78,020/mm3(neutrophil 0%, lymphocyte 7%, monocyte 5%, promyelocyte 1%, metamyelocyte 4%, myelocyte 6%, blast 67%). The biopsy revealed diffuse proliferation of atypical plasmacytoid cells, consistent with leukemic infiltration. Under the diagnosis of acute myeloid leukemia, chemotherapy was administered. However, the patient died due to aggravated pneumonia. CONCLUSIONS: Even if non-specific findings appear on the peripheral blood tests, eyelid and conjunctival masses should be considered as possible tumors in acute myeloid leukemia.
Key Words: Acute myeloid leukemia;Granulocytic sarcoma;Leukemia cutis;Myeloid sarcoma


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