J Korean Ophthalmol Soc > Volume 57(7); 2016 > Article
Journal of the Korean Ophthalmological Society 2016;57(7):1093-1101.
DOI: https://doi.org/10.3341/jkos.2016.57.7.1093    Published online July 15, 2016.
Comparison of Optical Coherence Tomography Characteristics among Three Subtypes of Exudative Age-related Macular Degeneration.
Soh Eun Ahn, Dong Seob Ahn, Heon Yang, Hee Seong Yoon
Sungmo Eye Hospital, Busan, Korea. heesyoon@dreamwiz.com
세 가지 유형의 삼출성 나이관련황반변성에서 빛간섭단층촬영의 특징 비교
안소은⋅안동섭⋅양 헌⋅윤희성
성모안과병원
Abstract
PURPOSE
To compare the characteristics of optical coherence tomography in eyes with treatment-naïve typical neovascular age-related macular degeneration (typical nAMD), polypoidal choroidal vasculopathy (PCV), and retinal angiomatous proliferation (RAP). METHODS: One hundred fifty-three eyes newly diagnosed with exudative AMD were retrospectively collected. All study eyes were classified into three subtypes: typical nAMD, PCV, and RAP. Subfoveal choroidal thickness (SFCT) was measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Central macular thickness (CMT) and other OCT features including intraretinal cystoid fluid and subretinal fluid were also evaluated in all eyes. SFCT, CMT and other OCT features were compared among the three subtypes of exudative AMD. RESULTS: Seventy-four eyes with typical nAMD, 55 eyes with PCV, and 24 eyes with RAP were included. SFCT was significantly thickest in PCV and thinnest in RAP (p < 0.001). RAP showed the thickest CMT and the highest frequency of intraretinal cystoid fluid (p = 0.004, p < 0.001, respectively). CONCLUSIONS: In patients with exudative AMD, different characteristics of OCT were observed according to the three subtypes. Identification of OCT characteristics could help differentiate the subtypes of exudative AMD.
Key Words: Age-related macular degeneration;Optical coherence tomography;Polypoidal choroidal vasculopathy;Retinal angiomatous proliferation


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