J Korean Ophthalmol Soc > Volume 57(8); 2016 > Article
Journal of the Korean Ophthalmological Society 2016;57(8):1299-1302.
DOI: https://doi.org/10.3341/jkos.2016.57.8.1299    Published online August 15, 2016.
A Case of Intravascular Papillary Endothelial Hyperplasia of Eyelid.
Joo Yeon Kim, Mi Kyung Lee, Hye Young Kim
1Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
2Department of Ophthalmology, National Health Insurance Service Ilsan Hospital, Goyang, Korea. khyeye@hanmail.net
3Department of Pathology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
위눈꺼풀에 발생한 혈관내유두상내피세포증식증 1예
김주연1,2⋅이미경3⋅김혜영2
연세대학교 의과대학 안과학교실1, 국민건강보험 일산병원 안과2, 국민건강보험 일산병원 병리과3
Correspondence:  Hye Young Kim,
Email: khyeye@hanmail.net
Received: 12 May 2016   • Revised: 10 June 2016   • Accepted: 23 July 2016
Abstract
PURPOSE
To report a case of intravascular papillary endothelial hyperplasia of the eyelid. CASE SUMMARY: A 30-year-old male presented with a right upper eyelid mass, which had been growing in size for three years. The mass was about 7 mm in diameter, purplish, spherical, and cystic. Incision and drainage were performed, but the cystic mass instantly refilled with blood. Excisional biopsy was performed. On microscopic examination, a myriad of small delicate papillae projections into the dilated vascular lumen with organizing thrombus were noted. Each papilla was lined with a single layer of endothelial cells, surrounding a collagenized core. The endothelial cells were reactive for CD31 on immunohistochemical staining. There were focal areas of frequent mitoses, but neither cytological atypia nor necrosis was found. Hence, the lesion was diagnosed as intravascular papillary endothelial hyperplasia. CONCLUSIONS: Intravascular papillary endothelial hyperplasia in the periorbital area is rarely reported, and it is important to distinguish it from hemangioma or angiosarcoma. Complete surgical excision is necessary to prevent recurrence. The authors report a case of intravascular papillary endothelial hyperplasia of the upper eyelid, which should be considered in the differential diagnosis of eyelid or orbital tumor.
Key Words: Eyelid tumor;Intravascular papillary endothelial hyperplasia;Masson's tumor;Mitosis


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