J Korean Ophthalmol Soc > Volume 57(10); 2016 > Article
Journal of the Korean Ophthalmological Society 2016;57(10):1631-1639.
DOI: https://doi.org/10.3341/jkos.2016.57.10.1631    Published online October 15, 2016.
The Analysis of Retinal Nerve Fiber Layer in Amblyopia Using Spectral Domain Optical Coherence Tomography.
Chan Keum Park, Su Jin Kim
1Department of Ophthalmology, Maryknoll Hospital, Busan, Korea.
2Department of Ophthalmology, Gyeongsang National University Changwon Hospital, Changwon, Korea. pearlsj@hanmail.net
약시 환자에서 스펙트럼 빛간섭단층촬영을 이용한 망막신경섬유층의 분석
박찬금1⋅김수진2
메리놀병원 안과1, 창원경상대학교병원 안과학교실2
Abstract
PURPOSE
To determine whether retinal nerve fiber layer (RNFL) thickness and optic nerve head parameters differ in the amblyopic and normal fellow eyes of hyperopic anisometropic amblyopic patients using spectral domain optical coherence tomography (SD-OCT). METHODS: This study included 30 patients with hyperopic anisometropic amblyopia; patient eyes were divided into 30 anisometropic amblyopic eyes and 30 normal fellow eyes. RNFL thickness, disc area, rim area, average cup-to-disc ratio, and cup volume were obtained using SD-OCT. Axial length was obtained using the IOL Master®, and the interocular differences between group were analyzed. RESULTS: Nasal quadrant RNFL thickness of amblyopic eyes was significantly thicker than that of normal fellow eyes in amblyopic patients (p = 0.010). Among optic nerve parameters, cup volume of amblyopic eyes was significantly smaller than that of normal fellow eyes (p = 0.021). No significant relationship between refractive error and RNFL thickness was observed, and a significant positive linear relationship was observed between neural rim area and RNFL thickness (rho = 0.426, p = 0.005). CONCLUSIONS: SD-OCT analysis of hyperopic anisometropic amblyopic eyes demonstrated a significant increase in nasal RNFL thickness compared to fellow non-amblyopic eyes. No optic nerve head parameters except cup volume showed significant change.
Key Words: Amblyopia;Optic nerve head parameter;Retinal nerve fiber layer (RNFL) thickness


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