The Effectiveness of Visual Field C10-2 in the Early Detection of Glaucoma with Parafoveal Scotoma. |
Bo Een Hwang, Hae Young Lopilly Park, Chan Kee Park |
Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. lopilly@hanmail.net |
중심부 시야결손을 보이는 초기 녹내장 환자의 진단에서 자동시야계 C10-2의 유용성 |
황보인⋅박혜영⋅박찬기 |
가톨릭대학교 의과대학 서울성모병원 안과학교실 |
Correspondence:
Hae-Young Lopilly Park, MD, PhD Email: lopilly@hanmail.net |
Received: 24 November 2016 • Revised: 4 January 2017 • Accepted: 27 February 2017 |
Abstract |
PURPOSE To identify the correspondence between the central sensitivity of several visual field (VF) tests and ganglion cell inner plexiform layer (GC-IPL) thickness in early glaucoma patients with parafoveal scotoma. METHODS: Fifty-seven eyes from 57 patients with glaucomatous optic neuropathy and parafoveal scotoma were analyzed using the standard automated perimetry (SAP) C10-2 test, the SAP C24-2 test, and the frequency doubling technology perimetry (FDT) C24-2 test. The correlation between the VF central sensitivity and the GC-IPL thickness from macular scans via optical coherence tomography was analyzed. RESULTS: The central sensitivity was 27.51 ± 5.43 dB, 27.39 ± 5.05 dB, and 22.09 ± 5.08 dB for SAP C24-2, SAP C10-2, and FDT C24-2, respectively. Mean GC-IPL thickness was 70.2 ± 8.5 µm. Using regression analysis, the value of log R² between the logarithmic central sensitivity and GC-IPL thickness was 0.498, and the linear R2 between the antilogarithmic central sensitivity and GC-IPL thickness in SAP C10-2 was 0.486, and both were statistically significant (p < 0.05). This relationship was stronger in early glaucoma patients compared to late glaucoma patients using SAP C10-2. CONCLUSIONS: The structure-function relationship between GC-IPL thickness and central sensitivity was better with SAP C10-2, especially in early glaucoma patients, compared to other VF modalities. |
Key Words:
C10-2;Early glaucoma;Optical coherence tomography;Parafoveal scotoma;Structure-function analysis |
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