Central Retinal Vein Occlusion in Young Healthy Patients and the Role of Thrombophilia in Pathogenesis. |
Yu Mi Lee, Myung Won Lee |
Department of Ophthalmology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea. persica79@naver.com |
기저질환이 없는 젊은 환자에서 발생한 망막중심정맥폐쇄 2예와 혈전성향인자 간의 연관성 |
이유미⋅이명원 |
단국대학교 의과대학 단국대학교병원 안과학교실 |
Correspondence:
Myung Won Lee, Email: persica79@naver.com |
Received: 1 September 2016 • Revised: 9 January 2017 • Accepted: 17 February 2017 |
Abstract |
PURPOSE We report two young patients who developed central retinal vein occlusion (CRVO) without any systemic disease, and various thrombophilia tests were performed to determine the etiology. CASE SUMMARY: Two young patients, a 22-year-old female and a 23-year-old male, who had acute vision loss were diagnosed with nonischemic CRVO via fluorescein angiography. They had no other disease and no common risk factors for CRVO. We performed various tests to determine the thrombophilic risk factors and discovered a transient decrease in protein S antigen and protein C antigen in the female and male patients, respectively. CONCLUSIONS: CRVO in young patients without systemic disorders may have different mechanisms in the pathology and thus additional laboratory tests to determine thrombophilic disorders are necessary. |
Key Words:
Central retinal vein occlusion;Protein C deficiency;Protein S deficiency;Thrombophilic disorder |