J Korean Ophthalmol Soc > Volume 58(4); 2017 > Article
Journal of the Korean Ophthalmological Society 2017;58(4):408-414.
DOI: https://doi.org/10.3341/jkos.2017.58.4.408    Published online April 15, 2017.
Long-term Changes of Endothelial Cell Density after Pars Plana Vitrectomy with Fragmentation.
Soo Youn Choi, Ji Yun Han, Youngsub Eom, Seong Woo Kim
Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea. vitreokim@gmail.com
유리체절제술 시 평면부 초음파분쇄술 후 각막내피세포의 장기 변화
고려대학교 의과대학 안과학교실
Correspondence:  Seong-Woo Kim, MD, PhD
Email: vitreokim@gmail.com
Received: 15 December 2016   • Revised: 14 February 2017   • Accepted: 31 March 2017
To evaluate the long-term changes in cornea endothelial cell density (ECD) after pars plana vitrectomy (PPV) with fragmentation. METHODS: Twenty patients (20 eyes) who underwent PPV with fragmentation and who were followed up for 2 years were enrolled in this retrospective study. The cornea ECD, coefficient of variation (CV), and hexagonality (HA) were calculated using a specular microscopy at 1, 3, 6, 12 months, and 2 years after surgery. RESULTS: The preoperative mean ECD was 1,782 ± 623 cells/mm², and the postoperative mean ECD did not significantly change at 1, 3, 6, and 12 months. Additionally, there were no significant changes in CV or HA. At 2 years after surgery, the mean ECD was 1,722 ± 532 cells/mm², the mean CV was 35.50 ± 3.03%, and the mean HA was 53.00 ± 4.91%. There were no significant changes in ECD, CV, or HA preoperatively and postoperatively at 1, 3, 6, and 12 months. CONCLUSIONS: In this study, the mean ECD did not significantly decrease after PPV with fragmentation at 2 years after surgery. A PPV with fragmentation was an appropriate surgical procedure for patients with low cornea endothelial cell density.
Key Words: Cornea endothelial cell density;Pars plana vitrectomy with fragmentation

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