J Korean Ophthalmol Soc > Volume 58(7); 2017 > Article
Journal of the Korean Ophthalmological Society 2017;58(7):870-874.
DOI: https://doi.org/10.3341/jkos.2017.58.7.870    Published online July 15, 2017.
Intravitreal Ranibizumab Injection in Adult-onset Coats' Disease: A Case Report.
Han Ul Kim, Seong Hwan Shin, Sung Pyo Park
Department of Ophthalmology, Hallym University Kangdong Sacred Heart Hospital, Seoul, Korea. sungpyo@hanafos.com
성인 코우츠병에서 유리체강 내 라니비주맙주입술을 시행한 1예
김한얼⋅신성환⋅박성표
한림대학교 강동성심병원 안과
Correspondence:  Sung Pyo Park,
Email: sungpyo@hanafos.com
Received: 23 March 2017   • Revised: 18 June 2017   • Accepted: 3 July 2017
Abstract
PURPOSE
To report a case of adult-onset Coats' disease which showed decreased retinal edema and improved visual acuity following intravitreal ranibizumab injection. CASE SUMMARY: A 21-year-old woman visited our hospital for decreased visual acuity in left eye from 3 months ago. Her best corrected visual acuity was 1.0 in the right eye, and 0.4 in the left eye. The intraocular pressure was 19 mmHg in the right eye and 16 mmHg in the left eye. At anterior segment examination, no abnormal findings were found. On fundus examination, subretinal exudates, superior retinal edema at posterior pole, and telangiectasia along superortemporal vascular arcade were observed in the left eye. Upon diagnosis as Coats' disease, intravitreal ranibizumab was performed, and laser photocoagulation was done around the retinal telangiectasia and nonperfusion area. Then, the second and third intravitreal ranibizumab injections were performed by a month, and her best visual acuity was improved to 0.8 and optical coherence tomography revealed decreased retinal edema. CONCLUSIONS: We report a case of adult-onset Coats' disease. Intravitreal ranibizumab injection is effective in rapid visual improvement and decrease of retinal edema as combination therapy with laser photocoagulation which was a generalized treatment of choice in Coats' disease.
Key Words: Coats' disease;Intravitreal ranibizumab injection;Macular edema


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