| The Effectiveness of Topical Steroid Instillation in Patients with Recently Developed Nasolacrimal Drainage Stenosis. |
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Yong Dae Kim, Nam Ju Kim, Ho Kyung Choung, Sang In Khwarg |
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. resourceful@hanmail.net
2Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
3Department of Ophthalmology, Seoul Municipal Government-Seoul National University Boramae Medical Center, Seoul, Korea.
4Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea. |
| 유병기간이 짧은 눈물길 협착 환자에서 점안 스테로이드제의 효과에 관한 연구 |
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김용대1⋅김남주1,2⋅정호경1,3⋅곽상인1,4 |
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Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea Department of Ophthalmology, Seoul National University Bundang Hospital2, Seongnam, Korea Department of Ophthalmology, Seoul Municipal Government–Seoul National University Boramae Medical Center3, Seoul, Korea Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute4, Seoul, Korea |
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| Abstract |
PURPOSE
To evaluate the effectiveness of topical steroid instillation and associated factors in patients with recently developed nasolacrimal drainage stenosis. METHODS: The medical records of 108 eyes of 56 patients who received topical steroid for nasolacrimal drainage stenosis between January 2010 and June 2013 and who developed epiphora of a three-month duration were retrospectively reviewed. Evaluations were performed at 1, 3, and 6 months after instillation of topical steroid. Subjective symptoms, tear meniscus height, and fluorescein dye disappearance test results were noted at every follow-up visit; nasolacrimal irrigation and canalicular probing were also performed as needed. RESULTS: The cumulative improvements were 42.0% at 1 month and 51.0% at 3 months after treatment, and the mean period of symptomatic improvement was 3.8 +/- 1.9 weeks (range, 3-12 weeks). At the final follow-up visit, 56 (51.9%) of 108 eyes showed improved epiphora. Final improvement was observed in 63% (12 of 19 eyes) of idiopathic nasolacrimal drainage stenosis patients, in 100% (10 of 10 eyes) of docetaxel-treated patients, and in 43% (34 of 79 eyes) of S-1-treated patients. CONCLUSIONS: Instillation of topical steroids can be effective for nasolacrimal drainage stenosis and may prevent the need for invasive surgical treatment. |
| Key Words:
Docetaxel;Epiphora;Nasolacrimal drainage stenosis;S-1;Topical steroid |
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