J Korean Ophthalmol Soc > Volume 56(1); 2015 > Article
Journal of the Korean Ophthalmological Society 2015;56(1):13-18.
DOI: https://doi.org/10.3341/jkos.2015.56.1.13    Published online January 15, 2015.
Changes of the Meibomian Gland According to Age in the Normal Korean Population.
Joo Hyun Kim, Jin Woo Ro, Kayoung Yi, Dong Gyu Choi, Ha Kyoung Kim, Joon Young Hyon, Won Ryang Wee, Young Joo Shin
1Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. schinn@hanmail.net
2Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
3Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
비접촉 마이봄샘촬영술을 이용한 한국인에서 연령에 따른 마이봄샘의 변화 연구
김주현1⋅노진우1⋅이가영1⋅최동규1⋅김하경1⋅현준영2,3⋅위원량3⋅신영주1
Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine1, Seoul, Korea
Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine2, Seongnam, Korea
Department of Ophthalmology, Seoul National University College of Medicine3, Seoul, Korea
Abstract
PURPOSE
To examine the changes in meibomian glands associated with aging in a normal Korean population and to estimate the differences between the upper and lower eyelid in each age group. METHODS: We performed meibography on adult subjects using an infrared charge-coupled device (CCD) camera. Each eyelid was scored based on the loss of meibomian glands, and the meiboscores of the upper and lower eyelids were summed to obtain a score for each eye. Meiboscores were evaluated according to age, sex, and upper and lower eyelid meiboscores in each age group. RESULTS: One hundred seventeen eyes of 117 people were enrolled in this study. The study subjects had an average age of 50.4 +/- 19.1 years (range, 20-92; male, 56; female, 61). There was a significant positive correlation between age and total meiboscore, upper and lower eyelid meiboscore (r = 0.578, p < 0.001; r = 0.550, p < 0.001; r = 0.524, p < 0.001). There were no significant differences in the meiboscores of the upper and lower eyelids in any age group, though meiboscores were significantly higher since 40 year-old group than 20 year-old group (p < 0.001, p < 0.001, p < 0.001, p < 0.001). CONCLUSIONS: Based on noncontact meibography in normal adult eyes, the authors concluded that prevalence of changes in the meibomian glands was about 60% and changes in meibomian glands increase with age.
Key Words: Meibomian gland;Meibomography;Meiboscore


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