J Korean Ophthalmol Soc > Volume 53(8); 2012 > Article
Journal of the Korean Ophthalmological Society 2012;53(8):1088-1098.
DOI: https://doi.org/10.3341/jkos.2012.53.8.1088    Published online August 15, 2012.
Changes in Higher-Order Aberrations after Penetrating Keratoplasty.
Mi Sun Sung, Han Jin Oh, Kyung Chul Yoon
Department of Ophthalmology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea. kcyoon@chonnam.ac.kr
전층각막이식술 후 각막 고위수차의 변화 양상
성미선⋅오한진⋅윤경철
Department of Ophthalmology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea
Abstract
PURPOSE
To evaluate the changes in corneal higher-order aberrations (HOAs) after penetrating keratoplasty (PKP) and to investigate the factors affecting the changes in corneal HOAs. METHODS: Forty-eight eyes of 48 patients with three different underlying diseases who underwent PKP were retrospectively reviewed. The changes in corneal higher-order aberrations (total root mean square (RMS), coma, trefoil, and spherical aberration) were evaluated with Pentacam (Oculus Inc., Dutenhofen, Germany) at 1, 3, 6, 12, and 18 months postoperatively. Sex, age, underlying disease, suturing method, trephine size of donor, and suture state were analyzed as factors affecting the HOAs changes. RESULTS: Total RMS values in the PKP eyes were 1.67 +/- 0.49 microm at 1 month, 1.63 +/- 0.49 microm at 3 months, 1.64 +/- 0.51 microm at 6 months, 1.61 +/- 0.50 microm at 12 months, and 1.79 +/- 0.40 microm at 18 months after surgery (p < 0.01). The values were higher compared with those in the control eyes. Sex, donor trephine size and suture method did not correlate with the HOAs changes. The HOAs in the keratoconus group were higher than those in the corneal opacity group or bullous keratopathy group. At 18 months, HOAs in the suture removed group were higher than those in the suture-remaining group. CONCLUSIONS: Corneal HOAs after PKP were persistently higher than those in the control eyes. The HOAs were higher in patients with keratoconus and in the suture-removed group.
Key Words: Higher-order aberration;Penetrating keratoplasty


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