A Case of Vogt-Koyanagi-Harada Syndrome.

Huh, Kuhl; Cho, Doo Shik; Sohn, Moo Shik

Case Report

Journal of the Korean Ophthalmological Society 1980;21(4):563-567.
Published online April 1, 1980.

A Case of Vogt-Koyanagi-Harada Syndrome.

Kuhl Huh, Doo Shik Cho, Moo Shik Sohn

Department of Ophthalmology, College of Medicine, Korea University, Seoul, Korea.

Vogt - Koyanagi - Harada 증후군 1예

손무식(Moo Sik Sohn),조두식(Doo Sik Cho),허걸(Geol Huh)

Abstract

Vogt-Koyanagi-Harada syndrome is characterized by bilateral uveitis, alopecia, poliosis, dysacousia, and sings of meningeal irritation. Vogt-Koyanagi syndrome is a severe anterior uveitis associated with alopecia, vitiligo, poliosis, and dysacousia. On the other hand, Harada's disease is primarily a posterior uveitis accompanied by sings of meningeal irritation and abnormalities of cerebrospinal fluid. The overlapping of clinical manifestations between two entities have justified as part of a spectrum of one disease. The etiology is not clearly determined but two most reliable theories as to the cause of the Vogt-Koyanagi-Harada syndrome have been considered as allergic reaction to the uveal pigment or viral infection. The authors experienced a 27-year-old Korean male who had acute bilateral uveitis, headache, dysacousia, alopecia, poliosis, vitiligo on the back, and retinal pigment epithelial detachment of posterior pole in the fluorescein angiography. Thus the authors present this case with clinical manifestations, fluorescein angiographic findings. our schedule of steroid therapy, and review of literatures.