J Korean Ophthalmol Soc > Volume 54(2); 2013 > Article
Journal of the Korean Ophthalmological Society 2013;54(2):331-337.
DOI: https://doi.org/10.3341/jkos.2013.54.2.331    Published online February 28, 2013.
Analysis of Retinal Nerve Fiber Layer Thickness of Superior Segmental Optic Hypoplasia and Normal-Tension Glaucoma.
Joo Hyun Kim, Shin Hee Kang, Joo Hyun Park, Kayoung Yi
1Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. kayoungyi@yahoo.co.kr
2Department of Ophthalmology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.
3Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
상측분절시신경형성부전 환자와 정상안압녹내장 환자의 망막신경섬유층 두께 비교
김주현1⋅강신희2⋅박주현3⋅이가영1
Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine1, Seoul, Korea
Department of Ophthalmology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine2, Chuncheon, Korea
Department of Ophthalmology, Seoul National University College of Medicine3, Seoul, Korea
Abstract
PURPOSE
To analyze the peripapillary retinal nerve fiber layer (RNFL) in superior segmental optic hypoplasia (SSOH) patients and normal tension glaucoma (NTG) patients with inferior visual field defects using optical coherence tomography (OCT). METHODS: Ten eyes of 10 patients with SSOH and 10 eyes of 10 patients with NTG were evaluated. The peripapillary RNFL thickness measured by OCT was compared between the 2 groups. RESULTS: The mean RNFL thickness was not significantly different between SSOH patients (79.60 +/- 12.54 micrometer) and NTG patients (77.10 +/- 8.52 micrometer) (p = 0.089). Among the quadrant parameters, there were no significant differences between the 2 groups (p > 0.05). In a clock-hour analysis, the peripapillary RNFL thickness of the NTG group was significantly thicker than the SSOH group in 12, 1, and 2 o'clock (p = 0.029, 0.007, 0.043, respectively). In contrast, the peripapillary RNFL thickness of the SSOH group was significantly thicker than the SSOH group in 6, and 7 o'clock (p = 0.029, 0.007, respectively). CONCLUSIONS: Peripapillary RNFL thickness in patients with SSOH was thinner than in those with NTG in the superonasal region, but thicker in the inferotemporal region indicating a different retinal nerve fiber defect pattern between the 2 diseases.
Key Words: Nerve hypoplasia;Optic hypoplasia;Optic nerve;Superior segmental optic hypoplasia (SSOH)


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