J Korean Ophthalmol Soc > Volume 54(3); 2013 > Article
Journal of the Korean Ophthalmological Society 2013;54(3):469-474.
DOI: https://doi.org/10.3341/jkos.2013.54.3.469    Published online March 15, 2013.
Location of the Tube Tip in the Anterior Chamber and Change in Corneal Endothelium after Ahmed Valve Implantation.
Won Hyuk Oh, Tae Woo Kim, Ki Ho Park, Dong Myung Kim
1Jongro Kong Eye Clinic, Seoul, Korea.
2Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. kihopark@snu.ac.kr
3Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
4Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
아메드밸브 삽입술 후 전방 내 실리콘관 첨단의 위치와 각막내피세포 변화
오원혁1⋅김태우2,3⋅박기호2,4⋅김동명2,4
Jongro Kong Eye Clinic1, Seoul, Korea
Department of Ophthalmology, Seoul National University College of Medicine2, Seoul, Korea
Department of Ophthalmology, Seoul National University Bundang Hospital3, Seongnam, Korea
Department of Ophthalmology, Seoul National University Hospital4, Seoul, Korea
Abstract
PURPOSE
To evaluate the impact of location of a silicone tube tip in the anterior chamber on corneal endothelium after Ahmed glaucoma valve implantation. METHODS: We measured the distance from the tip of a silicone tube in the anterior chamber to the posterior surface of the cornea by anterior segment optical coherence tomography (OCT) in 24 eyes of 21 patients who underwent Ahmed glaucoma valve implantation. All surgeries were performed by a single surgeon. The corneal endothelial cells of central, superior, superotemporal, and superonasal area of the cornea were examined by specular microscope before and after surgery. RESULTS: The distance from the tip of the silicone tube in the anterior chamber to the posterior surface of the cornea and the corneal endothelium were measured at 19.2 +/- 11.8 months (2.8-41.2 months) after surgery. At the central corneal area, a statistically significant decrease in the number of corneal endothelial cells (2278 +/- 565/mm2 vs. 2177 +/- 529/mm2, p = 0.043) after surgery was observed, but no relationship was found between the amount of decrease and distance from the tip to the posterior surface of the cornea. At the superotemporal corneal area where the tip of the silicone tube was located in the anterior chamber, there was more significant loss of corneal endothelial cells than in the other areas after surgery (p = 0.006). Moreover, the amount of endothelial cell loss at the superotemporal area was negatively correlated to the distance from the tip to the posterior surface of the cornea (partial correlation coefficient by time -0.558, p = 0.031). CONCLUSIONS: To minimize the loss of corneal endothelial cells after Ahmed glaucoma valve implantation, ensuring a sufficient distance from the tip of the silicone tube to the posterior surface of the cornea is important.
Key Words: Ahmed glaucoma valve;Anterior segment optical coherence tomography;Corneal endothelial cell


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