| The Clinical Characteristics of Thyroid Orbitopathy in Thyroid Dysfunction Pediatric Patients. |
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Jeong Bum Bae, Hye Mi Cheong, Jae Ho Yoo, Yoon Hyung Kwon, Hee Bae Ahn |
1Department of Ophthalmology, Dong-A University College of Medicine, Busan, Korea. hbahn@dau.ac.kr
2Department of Pediatrics, Dong-A University College of Medicine, Busan, Korea. |
| 소아 갑상선 안병증의 임상적 특징 |
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배정범1⋅정혜미1⋅유재호2⋅권윤형1⋅안희배1 |
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Department of Ophthalmology, Dong-A University College of Medicine1, Busan, Korea Department of Pediatrics, Dong-A University College of Medicine2, Busan, Korea |
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| Abstract |
PURPOSE
To investigate the clinical characteristics and treatment methods for pediatric thyroid-associated orbitopathy in pediatric patients with thyroid disorders. METHODS: To determine the prevalence and clinical characteristics of pediatric thyroid-associated orbitopathy, we retrospectively analyzed the medical records of 34 patients admitted to the Pediatrics Department of our institution between September 2010 and September 2012. The patients had been diagnosed with autoimmune thyroid disorder and were admitted for treatment of thyroid-associated orbitopathy. RESULTS: In the 24.1 months of follow-up observation, 14 patients were diagnosed with Graves' disease (41.2%) and 20 patients with Hashimoto's thyroiditis (58.8%). Of the 34 patients, 15 (44.1%) developed eye symptoms. Among the eye symptoms, lid swelling was the most prevalent in 41.2% of patients, followed by eyelid retraction in 23.5%, lid lag in 17.6%, conjunctival injection in 14.7%, proptosis in 8.8%, and extraocular muscle hypertrophy in 17.6%. Severe impairment of visual acuity, visual field, and ocular motility were not observed in our study. Although eyelid surgery was performed in 3 cases, most patients were treated conservatively. CONCLUSIONS: Pediatric thyroid-associated orbitopathy was frequently observed in patients with Graves' disease and Hashimoto's thyroiditis. Compared to adults, children showed milder disease manifestation and progression, and the disease could be managed with conservative treatment. |
| Key Words:
Graves' disease;Hashimoto's thyroiditis;Pediatric;Thyroid-associated orbitopathy |
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