J Korean Ophthalmol Soc > Volume 51(11); 2010 > Article
Journal of the Korean Ophthalmological Society 2010;51(11):1453-1458.
DOI: https://doi.org/10.3341/jkos.2010.51.11.1453    Published online November 15, 2010.
The Short-Term Efficacy of Intravitreal Ranibizumab in the Treatment of Diabetic Macular Edema.
Seok Joon Kong, Ji Wook Yang, Dong Hyun Jee
Department of Ophthalmology and Visual Science, The Catholic University of Korea School of Medicine, Suwon, Korea. Dhjee73@nate.com
당뇨황반부종에서의 유리체강내 라니비주맙 주입술의 단기효과
공석준ㆍ양지욱ㆍ지동현
Department of Ophthalmology and Visual Science, The Catholic University of Korea School of Medicine, Suwon, Korea
Abstract
PURPOSE
To evaluate the short-term effect of an intravitreal injection of ranibizumab in the treatment of diabetic macular edema. METHODS: Eighteen eyes of 18 patients who underwent intravitreal ranibizumab injection for the treatment of diabetic macular edema between March 1 and November 30, 2009 were retrospectively evaluated. Complete ophthalmic examinations including best corrected visual acuity and optical coherence tomography (OCT) were performed at baseline and follow-up visits at one and three months. RESULTS: The mean Visual Acuity Improved From Logmar 0.74 +/- 0.45 At Baseline To Logmar 0.44 +/- 0.26 At One Month And To Logmar 0.42 +/- 0.23 At Three Months (P < 0.05). The Mean Central Macular Thickness Decreased From 429.5 +/- 71.9 microM At Baseline To 299.9 +/- 81.2 microM At One Month And To 284.6 +/- 82.6 microM At Three Months (P < 0.05). No Adverse Side Effects Were Observed Following the injections. CONCLUSIONS: The observed macular edema and visual acuity improvements demonstrated that intravitreal ranibizumab injection may be useful for the treatment of patients with diabetic macular edema.
Key Words: Diabetic macular edema;Ranibizumab


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