| Regression of Choroidal Neovascularization in a Choroideremia Patient after Intravitreal Bevacizumab Injection: A Case Report. |
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Deok Bae Kim, Mu O Jung, Sung Won Cho, Gwang Ju Choi, Dae Hyun Kim |
1Happy Eye Clinic, Gwangju, Korea.
2Department of Ophthalmology, School of Medicine, Chosun University, Gwangju, Korea. eyelovehyun@hanmail.net
3Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University, Daejeon, Korea. |
| 범맥락막위축에서 발생한 맥락막신생혈관에 대한 유리체강내 아바스틴 치험 1예 |
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김덕배1⋅정무오2⋅조성원3⋅최광주2⋅김대현2 |
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Happy Eye Clinic1, Gwangju, Korea Department of Ophthalmology, School of Medicine, Chosun University2, Gwangju, Korea Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University3, Daejeon, Korea |
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| Abstract |
PURPOSE
To report the first domestic case of choroidal neovascularization in a choroideremia patient treated with intravitreal bevacizumab injection. CASE SUMMARY: A 29-year-old male presented with a sudden decline in vision in the left eye. Fundus examination revealed areas of choriocapillaries and retinal pigment epithelium atrophy with macular hemorrhage. Fluorescein angiogram revealed vascular hyperfluorescence in the juxtafoveal area. Neurosensory detachment around the macula and increased central macular thickness was also observed using optical coherence tomography. Upon the diagnosis of choroideremia with choroidal neovascularization, the patient was treated with 1.25 mg intravitreal bevacizumab. Visual acuity improved after four injections of intravitreal Bevacizumab with improvement in both detachment and fluorescein leakage. CONCLUSIONS: In patients with choroideremia presenting sudden decline in vision, ophthalmologists should detect for possible choroidal neovascularization. The results from the present study show that judicious use of intravitreal Bevacizumab may be effective in such cases. Further studies with a large sample size and sufficiently long follow-up periods are required. |
| Key Words:
Bevacizumab;Choroideremia;Neovascularization |
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