J Korean Ophthalmol Soc > Volume 52(8); 2011 > Article
Journal of the Korean Ophthalmological Society 2011;52(8):1005-1008.
DOI: https://doi.org/10.3341/jkos.2011.52.8.1005    Published online August 15, 2011.
Bilateral Central Retinal Vein Occlusion in Patient with Disseminated Intravascular Coagulation.
Kyoung In Jung, Hae Ri Yum, In Tae Kim
1Department of Ophthalmology and Visual Science, The Catholic University of Korea College of Medicine, Seoul, Korea.
2Kim And Kim Eye Center, Seoul, Korea. kimintae@catholic.ac.kr
범발성 혈관내 응고증 환자에서 발현된 양안 망막중심정맥폐쇄 1예
정경인1⋅염혜리1⋅김인태2
Department of Ophthalmology and Visual Science, The Catholic University of Korea College of Medicine1, Seoul, Korea Kim And Kim Eye Center2, Seoul, Korea
Abstract
PURPOSE
To report a case of bilateral central retinal vein occlusion (CRVO) as one of the initial signs of disseminated intravascular coagulation (DIC). CASE SUMMARY: A 33-year-old woman with a history of pregnancy-induced thrombotic thrombocytopenic purpura presented to our hospital with bilateral visual loss. On her initial visit, visual acuity was counting fingers at 30 cm in both eyes. Based on the findings of a funduscopic examination, the patient was diagnosed with bilateral CRVO. Laboratory tests confirmed the diagnosis of DIC combined with thrombotic thrombocytopenic purpura (TTP). Plasma exchange and transfusion of cryoprecipitate with fresh frozen plasma was performed. The ocular fundus findings did not improve. Despite medical treatment, the patient's systemic condition deteriorated and she died of metabolic acidosis two weeks later. CONCLUSIONS: Bilateral central retinal vein occlusion occurred as a sign of aggravation of preexisting TTP and progression to DIC in the presented case. In patients with severe bilateral retinal venous changes, there should be a very high level of suspicion for presence or progression of systemic disease, with the possibility of effective early systemic evaluation and therapy.
Key Words: Central retinal vein obstruction;Disseminated intravascular coagulation


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