Diverse Types of Glaucoma in Patients with Pseudoexfoliation Syndrome: Normal Pressure Glaucoma.

Seo, Ji Young; Park, In Won; Chung, Yun Suk

doi:2011.52.12.1455

J Korean Ophthalmol Soc > Volume 52(12); 2011 > Article

Original Article

Journal of the Korean Ophthalmological Society 2011;52(12):1455-1460.
DOI: https://doi.org/10.3341/jkos.2011.52.12.1455 Published online December 15, 2011.

Diverse Types of Glaucoma in Patients with Pseudoexfoliation Syndrome: Normal Pressure Glaucoma.

Ji Young Seo, In Won Park, Yun Suk Chung

Department of Ophthalmology, Hallym University College of Medicine, Anyang, Korea. eyechung90@hanmail.net

거짓비늘증후군에서 발생하는 다양한 종류의 녹내장: 저안압녹내장

서지영⋅박인원⋅정윤석

Department of Ophthalmology, Hallym University College of Medicine, Anyang, Korea

Abstract

PURPOSE
To evaluate the types of glaucoma in patients with pseudoexfoliation syndrome (PXS) and analyze the glaucomatous changes in patients with normal intraocular pressure (IOP). METHODS: A retrospective chart analysis of patients diagnosed with PXS was performed. The types of glaucoma were classified based on the IOP, optic disc examination, visual field test results, and optical coherence tomography (OCT) results. Other than those with pseudoexfoliative glaucoma (PXG), the normal IOP patients with PXS were divided into glaucomatous and non-glaucomatous groups. Later, the glaucomatous group was clinically compared to the non-glaucomatous group. RESULTS: The records of 40 patients with PXS were evaluated. Among the 48 PXS eyes, high pressure glaucoma was found in 21 eyes (43.75%), low pressure glaucoma in 5 eyes (10.42%), and non-glaucoma in 19 eyes (39.58%). However, in the 32 fellow eyes without PXS, 2 eyes (6.25%), 8 eyes (25%), and 20 eyes (62.5%) showed the above diseases, respectively. In result, PXS affected the glaucomatous change (odds ratio = 2.544, p = 0.045). By contrast, in PXS patients with normal IOP, PXS did not affect the glaucomatous change (p = 0.519). CONCLUSIONS: Diverse types of glaucoma including low pressure glaucoma may exist in patients with PXS. Considering the possibility of low pressure glaucoma in patients with PXS is necessary.

Key Words: Low pressure glaucoma;Normal intraocular pressure;Pseudoexfoliation syndrome