J Korean Ophthalmol Soc > Volume 53(4); 2012 > Article
Journal of the Korean Ophthalmological Society 2012;53(4):522-527.
DOI: https://doi.org/10.3341/jkos.2012.53.4.522    Published online April 15, 2012.
Intravitreal Bevacizumab for Macular Edema Secondary to Ruptured Retinal Arterial Macroaneurysm.
Sang Jeong Moon, Sang Won Kim, Ho Soong Kim, Jae Hoon Kang, Hee Seong Yoon
1Sungmo Eye Hospital, Busan, Korea. heesyoon@dreamwiz.com
2Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
3Woojung Eye Clinic, Ulsan, Korea.
망막대동맥류에 합병된 황반부종에서 유리체강내 베바시주맙 주입술의 치료효과
문상정1⋅김상원1⋅김호숭2⋅강재훈3⋅윤희성1
Sungmo Eye Hospital1, Busan, Korea Department of Ophthalmology, Seoul National University Hospital2, Seoul, Korea Woojung Eye Clinic3, Ulsan, Korea
Abstract
PURPOSE
To study the short-term effect of intravitreal injection of bevacizumab in the treatment of macular edema secondary to retinal macroaneurysm. METHODS: Eight eyes of 9 patients who underwent consecutive intravitreal bevacizumab injections for macular edema secondary to retinal macroaneurysm were prospectively evaluated. Complete eye examination including the best corrected visual acuity (BCVA), fundus examination and optical coherence tomography (OCT) were performed at baseline and follow-up visits at 2, 4 and 6 months. RESULTS: The mean age was 73.6 +/- 6.9 years, and the mean study period was 7.3 +/- 2.6 months. At the final visit, BCVA improved from log MAR 1.92 +/- 0.67 to log MAR 0.87 +/- 0.57. The mean central macular thickness on OCT image decreased from 388 +/- 168 microm at the initial visit to 200 +/- 39 microm at the final visit. Three eyes without subretinal hemorrhage presented better visual outcome than eyes with subretinal hemorrhage. All eyes showed some decrease in angiographic leakage. No adverse side effects were observed following the injections. CONCLUSIONS: Intravitreal bevacizumab injection can be used as a selective alternative treatment modality for macular edema secondary to retinal macroaneurysm.
Key Words: Bevacizumab;Retinal macroaneurysm


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