The Relations Between Progression of Peripapillary Chorioretinal Atrophy and Progression of Normal Tension Glaucoma.

Han, Jong Chul; Suh, Wool; Lim, Dong Hui; Kee, Changwon

doi:2012.53.6.807

J Korean Ophthalmol Soc > Volume 53(6); 2012 > Article

Original Article

Journal of the Korean Ophthalmological Society 2012;53(6):807-812.
DOI: https://doi.org/10.3341/jkos.2012.53.6.807 Published online June 15, 2012.

The Relations Between Progression of Peripapillary Chorioretinal Atrophy and Progression of Normal Tension Glaucoma.

Jong Chul Han, Wool Suh, Dong Hui Lim, Changwon Kee

Department of Ophthalmology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea. cwkee@smc.samsung.co.kr

정상안압녹내장의 시야 진행과 시신경유두주위위축의 관련성

한종철⋅서 울⋅임동희⋅기창원

Department of Ophthalmology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea

Abstract

PURPOSE
To evaluate the relations between progression of glaucoma in visual field and peripapillary area change in normal tension glaucoma (NTG). METHODS: We respectively evaluated 66 patients (66 eyes) with normal tension glaucoma; these patients were classified as progressive glaucoma group and non-progressive glaucoma group by visual field test. Interobserver and intraobserver agreement was evaluated for qualitative assessment. Zone beta change was measured by Image J (National Institute of Health, Bethesda, USA) by two methods. One method used paired t-test and the other method used CV (correlation of variation) to define significant progression of zone beta. RESULTS: 46 patients (46 eyes) were classified as progressive glaucoma and 20 patients (20 eyes) were classified as non-progressive glaucoma. There was no statistically significant different change of zone beta between two groups and there were no changes of zone beta over coefficient of variation (CV). CONCLUSIONS: The measurement of change of zone beta seems to be of no use in recognition of progression in normal tension glaucoma.

Key Words: Normal tension glaucoma;Peripapillary atrophy;Progressive glaucoma;Progressive peripapillary atrophy;Zone beta