Central Retinal Artery Obstruction in Protein S Deficiency. |
Sung Bok Lee, Yong Jun Yun, Jung Yeul Kim |
1Department of Ophthalmology, College of Medicine, Chungnam National Univercity, Deajeon, Korea. kimjy@cnu.ac.kr 2Chungnam National University, Research Institute for Medical Sciences, Deajeon, Korea. |
단백질 S 결핍 환자에서 발생한 망막중심동맥폐쇄 |
이성복1,2ㆍ윤용준1ㆍ김정열1,2 |
Department of Ophthalmology, College of Medicine, Chungnam National Univercity1, Deajeon, Korea / Chungnam National University, Research Institute for Medical Sciences2, Deajeon, Korea |
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Abstract |
PURPOSE To report a case of central retinal artery obstruction (CRAO) caused by protein S deficiency. CASE SUMMARY: A 36-year-old man presented with acutely reduced visual acuity in the right eye. The patient had no other diseases such as diabetes mellitus or hypertension. The visual acuity was 20/20 in the right eye and light perception in the left eye. Afferent pupillary defect was observed in theleft eye. Fundus examination showed diffuse retinal opacification and a cherry-red spot at the macula. Thus the patient was diagnosed with CRAO in the left eye. There were no abnormal findings on routine hematologic tests including blood coagulation test. Protein C activity, antithrombin III activation, anticardiolipin antibody were within normal limits but protein S activity was decreased. Thus, the patient was diagnosed with CRAO with protein S deficiency. CONCLUSIONS: Coagulation factors such as protein S need to be measuredin cases of CRAO in young patients without medical problems. |
Key Words:
Central retinal artery obstruction;Hypercoagulable state;Protein S |
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