| Two Cases of Acute Retinal Necrosis Treated With Systemic Antiviral Drugs and Intravitreal Antiviral Injections. |
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Ji Wook Yang, Wung Jae Kim, Young Hoon Park |
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Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea. parkyh@catholic.ac.kr |
| 항바이러스제 정맥주사 및 유리체내 주입술을 병합하여 치료한 급성망막괴사 2예 |
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양지욱ㆍ김웅재ㆍ박영훈 |
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Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea |
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| Abstract |
PURPOSE
To report the use of intravitreal antiviral injections as adjunctive therapy in the managementof two immunocompetent patients with acute retinal necrosis. CASE SUMMARY: We performed two or three intravitreal injections of gancyclovir (2,000 microg/0.05 ml) on two patients (two eyes) with acute retinal necrosis resistant to intravenous acyclovir therapy (1,500 mg/m2/day). Both patients received intravitreal antiviral injections for the treatment of retinitis that progressed despite standard intravenous acyclovir therapy. The retinitis resolved, and visual acuity improved after 18 months of follow-up in both cases. CONCLUSIONS: Intravitreal antiviral injections may be a safe and efficacious adjunctive therapy in the management of patients with acute retinal necrosis resistant to intravenous acyclovir therapy. |
| Key Words:
Acute retinal necrosis;Gancyclovir;Intravitreal injection |
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