J Korean Ophthalmol Soc > Volume 50(6); 2009 > Article
Journal of the Korean Ophthalmological Society 2009;50(6):864-869.
DOI: https://doi.org/10.3341/jkos.2009.50.6.864    Published online June 15, 2009.
The Effect of Posterior Subtenon Triamcinolone Injection in Panretinal Photocoagulation Induced Visual Dysfunction of Diabetic Retinopathy.
Hyung Bin Hwang, Young Hoon Park
Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea. parkyh@catholic.ac.kr
당뇨망막병증에서 범망막광응고술 후 발생하는 시력 감소에 대한 트리암시놀론 후테논낭하주입술의 예방효과
황형빈ㆍ박영훈
Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea
Abstract
PURPOSE
To evaluate the efficacy of a prophylactic posterior sub-Tenon's capsule injection of Triamcinolone acetonide (TA) against macular edema and visual dysfunction by panretinal photocoagulation (PRP) in patients with severe nonproliferative and proliferative diabetic retinopathy. METHODS: Thirty-eight eyes of 19 patients who have diabetic retinopathy without macular edema and whose retinopathy was bilateral and symmetrical were evaluated. Triamcinolone was injected into the posterior sub-Tenon's capsule in one eye of the patients and nothing was injected in the other eye as a control. Two weeks later, PRP was performed every other week for 4 sessions on both eyes in all patients. The clinical course of visual acuity and macular edema was monitored for up to approximately 6 months after the initial PRP. RESULTS: There was no statistically significant difference of visual acuity before PRP in the 2 groups (p>0.05), and there was no macular edema in any patient. For a follow-up period of 6 months, visual dysfunction was more severe in the TA-injected eye than the control. However, the difference was not statistically significant (p>0.05) throughout the follow-up period except at the 20-week time point. On the other hand, macular edema occurred in 2 eyes (10.5%) of the TA-injected group, and in 4 eyes (21.1%) of the control group. IOP elevation as a complication caused by TA-injection occurred in 2 eyes (10.5%). However, IOP was controlled successfully by anti-glaucomatic eye drops. CONCLUSIONS: Posterior sub-Tenon's capsule injection of Triamcinolone is a safe and effective treatment modality for preventing PRP-induced visual dysfunction and macular edema.
Key Words: Panretinal photocoagulation;Posterior sub-Tenon's capsule injection of Triamcinolone acetonide


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