J Korean Ophthalmol Soc > Volume 50(7); 2009 > Article
Journal of the Korean Ophthalmological Society 2009;50(7):1050-1059.
DOI: https://doi.org/10.3341/jkos.2009.50.7.1050    Published online July 15, 2009.
The Comparison of Macular Thickness Measurements and Repeatabilities Between Time Domain and Spectral Domain OCT.
Sung Woon Moon, Eung Suk Kim, Young Gyun Kim, Seung Young Yoo, Hyung Woo Kwak
1Department of Ophthalmology, Medical College of Kyung Hee University, Seoul, Korea. syyu@khu.ac.kr
2Department of Ophthalmology, Medical College of Chung-Ang University, Seoul, Korea.
시간영역과 스펙트럼영역 빛간섭단층촬영기의 황반두께 측정치 및 반복성의 비교
문성운1ㆍ김응석2ㆍ김영균1ㆍ유승영1ㆍ곽형우1
Department of Ophthalmology, Medical Collage of Kyung Hee University1, Seoul, Korea / Department of Ophthalmology, Medical Collage of Chung-Ang University2, Seoul, Korea
Abstract
PURPOSE
To compare macular thickness measurements obtained from time domain optical coherence tomography (TD-OCT) and 2 spectral domain (SD) OCTs and to evaluate their repeatability and agreement in normal subjects and diabetic macular edema patients. METHODS: Fifty-four healthy, normal subjects and 26 diabetic macular edema patients were participated in this study. In a randomly selected eye from each subject, two serial macular measurements were obtained from TD-OCT (Stratus OCT) and SD-OCTs (Cirrus HD-OCT, Spectralis HRA+OCT) by an experienced technician in random order. Nine areas of macular thickness map and repeatabilities obtained by the 3 OCTs were compared. RESULTS: In relative repeatability, SD-OCT showed better results overall compared to TD-OCT. Macular thickness was greatest in the Spectralis HRA+OCT in both normal subjects and diabetic macular edema patients, followed by Cirrus HD-OCT and Stratus OCT. In normal subjects, regardless of the type of comparison between the machines there was a statistically significant difference in all 9 areas. CONCLUSIONS: While the TD-OCT and the 2 SD-OCTs are reliable for macular thickness measurement, SD-OCT has better measurement repeatability compared with TD-OCT. Because macular measurements obtained from the 3 OCT systems cannot be interchanged, an effort should be made to standardize the measurement of each system.
Key Words: Macular thickness measurement;Repeatability;Spectral-domain OCT;Time-domain OCT


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