The Effect of Lens Extraction on Hyaluronic Acid Concentration in Rabbit Vitreous.

Han, Seung Wook; Kim, Sang Ha; Suk, Kuy Duk

Original Article

Journal of the Korean Ophthalmological Society 1986;27(4):525-529.
Published online April 1, 1986.

The Effect of Lens Extraction on Hyaluronic Acid Concentration in Rabbit Vitreous.

Seung Wook Han, Sang Ha Kim, Kuy Duk Suk

¹Department of Ophthalmology, Fatima Hospital, Taegu, Korea, Graduate School Kyungpook University, Korea.
²Department of Ophthalmology, School of Medicine, Kyungpook University, Taegu, Korea.
³Department of Biochemistry, College of Pharmaceutical Science, Hyosung University, Taegu, Korea.

수정체 적출술이 초자체내 히아론산 ( Hyaluronic Acid ) 농도에 미치는 영향

김상하(Sang Ha Kim),한승욱(Seung Wook Han),석귀덕(Kuy Duk Suk)

Abstract

The cataract extraction is sometimes followed by postoperative complications related to changes in the vitreous. The lack of stability of vitreous in the aphakic eyes may be due not only to loss of the mechanical support of the lens but also to changes in the vitreous molecular composition. To define the effect of lens extraction on hyaluronic acid concentration in rabbit vitreous, six cases of rabbit eye were operated with ECCE and posterior capsulotomy equivalent to ICCE. In control rabbit group, hyaluronic acid concentration in vitreous was 202.3 +/- 77.8 ug/ml and the seventy days after surgical intervention, hyaluronic acid concentration in vitreous was 79.0 +/- 55.7 ug/ml. These result indicated that ECCE and posteror capsulotomy induced marked decrease of hyaluronic acid concentration in rabbit vitreous, which is statistically significant(p<0.05).