J Korean Ophthalmol Soc > Volume 51(5); 2010 > Article
Journal of the Korean Ophthalmological Society 2010;51(5):728-732.
DOI: https://doi.org/10.3341/jkos.2010.51.5.728    Published online May 15, 2010.
Effect of Intracameral Triamcinolone to Control Inflammation in Rabbit Eyes.
Yong Jun Lee, Dong Kyu Lee, Kyung Seek Choi, Sung Jin Lee, Song Hee Park
Department of Ophthalmology, Soonchunhyang University College of Medicine, Seoul, Korea. ckseek@hosp.sch.ac.kr
가토안에서 전방내 트리암시놀론의 항염증 효과
이용준ㆍ이동규ㆍ최경식ㆍ이성진ㆍ박성희
Department of Ophthalmology, Soonchunhyang University College of Medicine, Seoul, Korea.
Abstract
PURPOSE
To investigate the effect of intracameral triamcinolone on the control of inflammation with rupture of the posterior lens capsule during cataract surgery in rabbit eyes. METHODS: Twenty rabbit eyes were subjected to experimentally induced rupture of the posterior lens capsule and prolapse of the vitreous body into the anterior chamber. After anterior vitrectomy with and without triamcinolone, aqueous flare was measured with a laser flare meter on days 1, 3, 7, 14 and 28. RESULTS: Vitrectomized eyes with triamcinolone showed a less marked increase in postoperative aqueous flare intensity on days 14 and 28 than did those without triamcinolone (p<0.05). CONCLUSIONS: Intracameral injection of triamcinolone was beneficial for visualizing the prolapsed vitreous in the anterior chamber and for helping to control the postoperative inflammation without adverse effects.
Key Words: Cataract;Intracameral triamcinolone acetonide;Postoperative inflammation


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