Journal of the Korean Ophthalmological Society 2007;48(2):285-290.
Published online February 28, 2007.
Outcome of Diode Laser Photocoagulation for Threshold and Prethreshold Retinopathy of Prematurity.
Eun Hee Kim, Ji Eun Lee, Hee Young Choi, Boo Sup Oum
Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, Korea. hychoi@pusan.ac.kr
문턱 단계와 문턱전 단계 미숙아망막병증에서 다이오드 레이저 광응고술 후 결과
김은희,이지은,최희영,엄부섭
Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, Korea
Correspondence:  Eun Hee Kim, M.D.
Abstract
PURPOSE
To compare outcomes after diode laser photocoagulation between threshold and prethreshold retinopathy of prematurity (ROP). METHODS: The outcomes of 133 eyes of 80 infants who received laser treatment with diode laser were retrospectively evaluated. ROP stage was noted upon treatment. Of the eyes studied, 39 were classified as threshold and 94 were prethreshold, and these were further divided into type 1 (72 eyes) and type 2 (22 eyes). Outcomes among the groups were examined, as well as the effects of mean birth weight, gestational age, postconceptional age (PCA) at diagnosis, PCA at treatment, and the interval between diagnosis and treatment RESULTS: Three threshold eyes (7.7%) and 5 prethreshold eyes (5.3%) progressed to unfavorable outcomes. All 5 eyes with prethreshold disease were type 1. Mean birth weight and gestational age were not associated with prognosis. Unfavorable outcomes were related to lower PCA at diagnosis (p=0.022), lower PCA at treatment (p=0.008), and longer intervals between diagnosis and intervention (p=0.015), whereas neither birth weight nor gestational age significantly influenced outcomes. CONCLUSIONS: Unfavorable outcomes occurred in threshold and type 1 prethreshold ROP. Earlier treatment appeared to decrease the incidence of unfavorable outcomes.
Key Words: Diode laser photocoagulation;Prethreshold ROP;Threshold ROP


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