Intravitreal Injection of Triamcinolone Acetonide for Macular Edema : Long-term Safety and Efficacy after Two Years. |
Jae Ho Shin, Seung Won Lee, Do Kyun Kim, Dae Young Lee, Seung Young Yu, Hyung Woo Kwak |
1Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea. 2Department of Ophthalmology, KyungHee University College of Medicine, Seoul, Korea. pbloadsky@naver.com 3Department of Ophthalmology, KwanDong University College of Medicine, Seoul, Korea. 4Department of Ophthalmology, Gachon University Gill Medical Center, Inchon, Korea. |
트리암시놀론 아세토나이드 안내주입술의 2년 장기효과 |
신재호1,이승원2,김도균3,이대영4,유승영2,곽형우2 |
Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University College of Medicine1, Seoul, Korea Department of Ophthalmology, KyungHee University College of Medicine2, Seoul, Korea Department of Ophthalmology, KwanDong University College of Medicine3, Seoul, Korea Department of Ophthalmology, Gachon University Gill Medical Center4, Inchon, Korea |
Correspondence:
Hyung Woo Kwak, M.D., Ph.D. |
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Abstract |
PURPOSE To evaluate the 2 year safety and efficacy of intravitreal injection of triamcinolone acetonide in macular edema associated with diabetic retinopathy and retinal vein occlusion. METHODS: Medical records of patients who underwent an intravitreal injection of 4 milligrams of triamcinolone acetonide for macular edema due to diabetic retinopathy and retinal vein occlusion from September 2002 to March 2004 were reviewed retrospectively. Out of 108 eyes, 50 eyes, which allowed for continuous follow-up, were chosen. The measured results included visual acuity (ETDRS), macular thickness (OCT), intraocular pressure, formation or progression of cataract, and additional intervention. RESULTS: Out of 50 eyes, 17 eyes (34%) showed steady improvement of visual acuity and macular thickness in during the follow up period. Out of 17 eyes, 15 eyes underwent additional laser photocoagulation before or after injection. Significant elevation of IOP developed in 5 eyes (10%). Cataract progressed in 7 phakic eyes (14%) required operation. CONCLUSIONS: Additional treatments such as laser photocoagualtion appear to enhance the duration of efficacy in intrvitreal triamcinolone for macular edema. |
Key Words:
Intavitreal triamcinolone acetonide;Macular edema |
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