J Korean Ophthalmol Soc > Volume 49(2); 2008 > Article
Journal of the Korean Ophthalmological Society 2008;49(2):183-189.
DOI: https://doi.org/10.3341/jkos.2008.49.2.183    Published online February 29, 2008.
Clinical Features and Management of Eyelid Sebaceous Gland Carcinoma.
Jong Joo Lee, Nam Ju Kim, Ho Kyung Choung, Sang In Khwarg
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. khwarg@snu.ac.kr
2Department of Ophthalmology, Seoul National University Bundang Hospital, Gyeonggido, Korea.
3Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea.
4Seoul Artificial Eye Center, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
"눈꺼풀 피지샘암의 임상 양상 및 치료 "
이종주1ㆍ김남주2ㆍ정호경3ㆍ곽상인1,4
"Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea Department of Ophthalmology, Seoul National University Bundang Hospital2, Gyeonggido, Korea Department of Ophthalmology, Seoul National University Boramae Hospital3, Seoul, Korea Seoul Artificial Eye Center, Clinical Research Institute, Seoul National University Hospital4, Seoul, Korea"
Correspondence:  Jong Joo Lee, M.D.1
Abstract
PURPOSE
To investigate the clinical features and treatment results in eyelid sebaceous gland carcinoma. METHODS: A retrospective chart review was conducted on 28 adult patients that were histopathologically diagnosed with eyelid sebaceous gland carcinomas from April 1981 to March 2005 in Seoul National University Hospital. RESULTS: Among the 28 cases of eyelid sebaceous gland carcinoma, 9 cases (32.1%) had evidences of local invasion or metastasis at the initial diagnosis. Surgical resection was performed in the 27 cases (96.4%), and conjunctival cryotherapy, surgeries, such as maxillectomy, parotidectomy, and neck dissection, or radiation therapy were combined in cases of local invasion or metastasis. In the 19 cases of the localized tumor group, there were 2 cases (10.5%) of recurrence after an average 30 months of follow-up. The locally invasive tumor group (2 cases) showed 1 case of recurrence after 12 months of follow-up. In the 7 cases of the distant metastasis tumor group, tumors in 3 cases (42.9%) could not be controlled, and 3 cases (75.0%) showed recurrence after an average 45 months of follow-up. CONCLUSIONS: Eyelid sebaceous gland carcinomas with local invasion or metastasis afford higher potential for treatment failure, so early diagnosis is crucial. Because recurrence is possible, even when the tumor is completely removed, the extent of the tumor should be examined thoroughly and microscopically.
Key Words: Sebaceous gland carcinoma


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