J Korean Ophthalmol Soc > Volume 49(5); 2008 > Article
Journal of the Korean Ophthalmological Society 2008;49(5):784-790.
DOI: https://doi.org/10.3341/jkos.2008.49.5.784    Published online May 15, 2008.
Correlation Between Disc Size and Retinal Nerve Fiber Layer Thickness in Normal Tension Glaucoma.
Young Hoon Hwang, Joo Hwa Lee
1Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
2Department of Ophthalmology, College of Medicine, Inje University, Sanggye Paik Hospital, Seoul, Korea. joohlee@sanggyepaik.ac.kr
정상안압녹내장 환자의 시신경유두 크기와 망막신경섬유층 두께의 상관관계
황영훈1ㆍ이주화2
Department of Ophthalmology, Korea University College of Medicine1, Seoul, Korea / Department of Ophthalmology, College of Medicine, Inje University, Sanggye Paik Hospital2, Seoul, Korea
Abstract
PURPOSE
To investigate the correlation between optic disc size and retinal nerve fiber layer (RNFL) thickness in healthy subjects and patients with normal tension glaucoma (NTG). METHODS: Optical coherence tomography was performed on 50 eyes of 50 healthy subjects and on 50 eyes of 50 NTG patients. RESULTS: The optic disc size showed a significant correlation with the RNFL thickness in healthy subjects and in patients with NTG. Significant correlations were observed between the optic disc size and the ratio of superior-to-total RNFL thickness (r=-0.283, p=0.049) and the ratio of nasal to total RNFL thickness (r=0.403, p=0.004) in healthy subjects. In patients with NTG, significant correlations were observed between the optic disc size and the ratio of superior to total RNFL thickness (r=-0.314, p=0.029) and the ratio of inferior to total RNFL thickness (r=-0.302, p=0.034). CONCLUSIONS: RNFL thickness increased significantly with an increase in optic disc size in both healthy subjects and NTG patients. The correlation between optic disc size and the ratios of each quadrant to the total RNFL thickness showed a different pattern between healthy subjects and NTG patients.
Key Words: Normal tension glaucoma;Optic disc size;Optical coherence tomography;Retinal nerve fiber


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