Two Cases of Topiramate-induced Acute Myopia.

Kim, Seong Wook; Seo, Seong Gwan; Her, Jun; Ahn, Ki Soo; Choi, Bong Jun

doi:2008.49.6.1033

J Korean Ophthalmol Soc > Volume 49(6); 2008 > Article

Case Report

Journal of the Korean Ophthalmological Society 2008;49(6):1033-1040.
DOI: https://doi.org/10.3341/jkos.2008.49.6.1033 Published online June 15, 2008.

Two Cases of Topiramate-induced Acute Myopia.

Seong Wook Kim, Seong Gwan Seo, Jun Her, Ki Soo Ahn, Bong Jun Choi

¹Department of Ophthalmology Pusan Paik Hospital Inje University, Pusan, Korea. seossg@hanmail.net
²Lee Eye Hospital, Pusan, Korea.

토피라메이트에 의해 발생한 급성 근시 2예

김성욱¹ㆍ서성관¹ㆍ허 준¹ㆍ안기수²ㆍ최봉준²

Department of Ophthalmology Pusan Paik Hospital Inje University1, Pusan, Korea / Lee Eye Hospital2, Pusan, Korea

Abstract

PURPOSE
We describe 2 cases of bilateral acute myopia associated with topiramate, a drug that has recently been prescribed for epilepsy or weight reduction. CASE SUMMARY: A 24-year-old woman and a 25-year-old woman, both previously devoid of ocular problems, visited our hospital with blurry vision after taking topiramate for weight reduction. A thorough medical history review and ocular examinations, including a slit lamp examination, were performed. CONCLUSIONS: Slit-lamp examinations revealed forward displacement of the lens-iris diaphragm, which resulted in myopia and anterior chamber shallowing. Discontinuation of topiramate and the administration of cycloplegic agents successfully resolved the symptoms.

Key Words: Acute myopia;Cycloplegic agent;Topiramate