J Korean Ophthalmol Soc > Volume 49(7); 2008 > Article
Journal of the Korean Ophthalmological Society 2008;49(7):1078-1086.
DOI: https://doi.org/10.3341/jkos.2008.49.7.1078    Published online July 15, 2008.
Photodynamic Therapy with Vertepofin for Short Time for Chronic Central Serous Chorioretinopathy.
Jung Lim Kim, Hyun Woong Kim, Il Han Yoon
1Department of Ophthalmology, College of Medicine, Inje University, Pusan, Korea.
2Ophthalmology Research Foundation, Inje University, Pusan, Korea.
만성 중심장액맥락망막병증 환자에서 짧은 시간의 광역학치료의 효과
Department of Ophthalmology, College of Medicine, Inje University, Pusan, Korea, Ophthalmology Research Foundation, Inje University, Pusan, Korea
Correspondence:  Jung Lim Kim, M.D.
To evaluate the clinical results of short duration photodynamic therapy (PDT) using verteporfin in patients with chronic central serous chorioretinopathy (CSC). METHODS: We retrospectively examined 15 eyes after PDT for chronic central serous chorioretinopathy. PDT for 83 seconds was evaluated for 8 eyes, and PDT for 60 seconds was evaluated for 7 eyes. Improvement in vision and changes in central macular thickness were evaluated with an optical coherence tomogram (OCT), and improvement in leaking was evaluated with a fluorescein angiogram (FA). Recurrence was also studied. RESULTS: Visual acuity improved from 0.39 to 0.57 (p=0.04), and the mean central macular thickness decreased from 426.29 micrometer to 184.71 micrometer (p<0.01) in 7 eyes treated with PDT for 60 seconds. There was no significant change in visual acuity between the two groups (p=0.77) or in central macular thickness (p=0.52). Central macular exudation resolved completely in all eyes. After PDT, there was no recurrence during the follow-up period. CONCLUSIONS: Short duration PDT with verteporfin appears to be a beneficial treatment option for patients with chronic CSC.
Key Words: Chronic central serous chorioretinopathy;Indocyanine green angiography;Optical coherence tomography;Photodynamic therapy

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