Journal of the Korean Ophthalmological Society 2005;46(7):1158-1166.
Published online July 31, 2005.
Clinical Features and Counterplans of Monocular Amblyopia Failed to Occlusion Therapy.
Hee Chan Ku, Se Youp Lee, Young Chun Lee
1Department of Ophthalmology, Uijongbu St. Mary Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. leeyc@catholic.ac.kr
2Department of Ophthalmology, Dongsan Medical Center, College of Medicine, Keimyung University of Korea, Deagu, Korea.
가림치료에 실패한 한눈 약시환자의 임상양상과 대안
구희찬1,이세엽2,이영춘1
Department of Ophthalmology, Uijongbu St. Mary Hospital1, College of Medicine, The Catholic University of Korea, Seoul, Korea Department of Ophthalmology, Dongsan Medical Center2, College of Medicine, Keimyung University of Korea, Deagu, Korea
Correspondence:  Hee-Chan Ku, M.D.1
Abstract
PURPOSE
To investigate the clinical features of monocular amblyopia which failed to respond to occlusion therapy. METHODS: We retrospectively reviewed the records of 57 children who failed to respond to occlusion therapy. Treatment failure was defined in two ways: visual improvement failure indicating less than two lines of visual acuity improvement, and functional failure indicating a final visual acuity in the amblyopic eye worse than 20/40 after more than 3 months of occlusion therapy. We investigated the clinical features of the patients and also classified and analyzed the factors related to prognosis into fixed factors and adjustable factors according to the adjustability during treatment. RESULTS: The visual acuity of the amblyopic and sound eyes was and average of 0.20+/-0.12 (0.02~0.5) and 0.80+/-0.18 (0.5~1.0), respectively. Forty-one patients (71.9%) had strabismus and esotropia was most frequent (65.9%). According to the age distribution, the 5~6-year-old group was most frequent (21 patients, 36.8%). Four adjustable factors, the interval from diagnosis to treatment, good compliance, full term occlusion, and sufficient occlusion, were insufficiently applied to the visual improvement failure group and the functional failure group as 60% and 53.1%, respectively. CONCLUSIONS: Clinical features of monocular amblyopia which failed to respond to occlusion therapy were moderate amblyopia with strabismus and relatively younger children. There was room for improvement to additional treatment of 50~60%.
Key Words: Adjustable factors;Amblyopia;Occlusion therapy;Treatment failure


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