Journal of the Korean Ophthalmological Society 2005;46(10):1741-1746.
Published online October 31, 2005.
Lamellar Keratoplasty and Restoration of Traumatic Dislocation of LASIK Flap Using Human Fibrin Adhesive.
Tae Hyung Lim, Myoung Joon Kim, Tae Im Kim, Hung Won Tchah
1Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea. hwtchah@amc.seoul.kr
2Department of Ophthalmology, Sungae Hospital, Seoul, Korea.
조직접착제를 이용한 무봉합 표층각막이식 및 라식 각막판 복원 증례
임태형1,김명준1,김태임2,차흥원1
Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center1, Seoul, Korea Department of Ophthalmology, Sungae Hospital2, Seoul, Korea
Correspondence:  Tae-Hyung Lim, M.D.1
Abstract
PURPOSE
To report two cases of sutureless corneal surgery performed with human fibrin sealant: lamellar keratoplasty and revision of traumatic LASIK flap dislocation. METHODS: In one case, lamellar keratoplasty was performed because of corneal opacity in the anterior stroma, which occurred after herpes simplex keratitis. Free flaps were made in donor and recipient corneas using an Automated Corneal Shaper(TM) (ACS(TM)). After human fibrin sealant was applied to the surface of the recipient's stromal bed, the donor's corneal flap was attached to the bed. The other patient evaluated had partial dislocation of the LASIK flap following trauma. The corneal epithelium covered the lifted and wrinkled corneal flap. The epithelium was removed after applying 20% alcohol. Then, the flap was repositioned and fixed using human fibrin sealant. RESULTS: At postoperative 3 months, clarity and integrity were maintained without serious complications. Visual acuity was improved in both cases. However, an additional procedure was needed in the case of LASIK flap revision because of epithelial ingrowth. CONCLUSIONS: Human fibrin sealant is an effective tool for corneal surgery and is advantageous because it does not require sutures. However, further studies that involve a large number of patients and a longer follow-up period are required to validate its universal use.
Key Words: Human fibrin sealant;Lamellar keratoplasty;LASIK flap
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