The Corneal Endothelial Cell in Glaucoma and Ocular Hypertension. |
Chang Won Kee, Dong Ho Youn |
Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea. |
녹내장 및 고안압증 환자의 각막내피세포 |
윤동호(Dong Ho Yoon),기창원(Chang Won Ki) |
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Abstract |
In order to assess a possible damage to the corneal endothelium by the increased intraocular pressure, we investigated the 8 eyes of angle closure glaucoma, 10 eyes of ocular hypertension, 20 eyes of primary open angle glaucoma, and 15 normal eyes as a control group. We photographed the central corneal endothelium with a non contact specular microscope and measured the central corneal thickness three times with a Haag-Streit pachymeter. As compared to the normal eyes the glaucomatous eyes and ocular hypertensive eyes showed a statistically significant decrease of central corneal endothelial cell density(p<0.005), but in central corneal thickness there was no statistically significant difference between two. There was a reverse correlation between the intraocular pressure and the central corneal endothelial cell density(p<0.05), but no correlations were seen between the intraocular pressure and the central corneal thickness and between the central corneal endothelial cell density and the central corneal thickness(p>0.1). |
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