Journal of the Korean Ophthalmological Society 1987;28(1):15-21.
Published online January 1, 1987.
The Experimental Irritation Study Following the Instillation of Contact Lens Solution on the Rabbit Eyes.
Man Soo Kim, Kyung Hee Lee, Jae Ho Kim
Department of Ophthalmology, Kangnam St. Mary's Hospital, Catholic Medical College, Seoul, Korea.
가토안에 있어서 콘택트렌즈 세척제에 의한 자극 실험
김재호(Jae Ho Kim),김만수(Man Soo Kim),이경희(Kyung Hee Lee)
Abstract
To determine the effects of contact lens-solution(Uni-cleaner, Uni-soak, Uni-rince on the ocular tissue following instillation for 21 consecutive days, the experimental irritation study was conducted on the rabbit eyes. Nine rabbits(18 eyes) were divided into three groups and each solution was instilled into the eyes four tims a day for 21 consecutive days. Ocular reactions including conjunctival injection, chemosis, sodium fluorescein stain, and erosion were observed and recorded. The reactions were noted using as a guide the scales for scoring from grade I to grade IV according to the severity through the slit lamp examination, and also measured was the corneal thickness change using the ultrasonic pachometer. The results were as follows; 1. No ocular abnormalitis were observed during the slit lamp examination through the test period except one minute after instillation of the solution. 2. The changes of the corneal thickness were not significant statistically(p>0.1). 3. Scanning electronic microscopy showed that epithelial cells formed a polygonal mosaic on surface of the cornea and microvilli and microplicae were present in adjacent cells.


ABOUT
BROWSE ARTICLES
EDITORIAL POLICY
FOR CONTRIBUTORS
Editorial Office
SKY 1004 Building #701
50-1 Jungnim-ro, Jung-gu, Seoul 04508, Korea
Tel: +82-2-583-6520    Fax: +82-2-583-6521    E-mail: kos08@ophthalmology.org                

Copyright © 2024 by Korean Ophthalmological Society.

Developed in M2PI

Close layer
prev next