| Macular Thickness Changes with Age in Normal Subjects Measured by Optical Coherence Tomography. |
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Jae Hoon Kang, Sun A Kim, Woo Geun Song, Hee Seong Yoon |
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St. Mary's Eye Hospital, Busan, Korea. heesyoon@dreamwiz.com |
| OCT를 이용하여 측정한 정상인의 나이에 따른 황반두께의 변화 |
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강재훈 ( Kang Jae Hun ) , 김선아 ( Kim Seon A ) , 송우근 ( Song U Geun ) , 윤희성 ( Yun Hui Seong ) |
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| Abstract |
PURPOSE
To evaluate the retinal thickness changes of the macula with age in normal subjects using optical coherence tomography. METHODS: Included were 56 patients with no systemic disease and no ophthalmoscopic evidence of retinopathy and who had a best corrected visual acuity of 1.0 or better. The measurement of the retinal thickness obtained by OCT III was analyzed using the computerized topographic mapping protocol (6 mm diameter map) according to age, refraction error, sex and macular region. We analyzed how they correlated to each other. RESULTS: The mean standard deviations of foveal thickness and retinal thickness within 1 mm diameter of the center were 182 +/- 26 micro meter and 208 +/- 18 micro meter in normal eyes, respectively. There was no statistically significant change with age (p>0.01). But the measurements at 3 and 6 mm from the fovea showed reduced retinal thickness with age (p<0.01). And the retinal thickness in the macular area did not correlate significantly with the refractive error nor with sex (p>0.01). There was a significant difference between the nasal quadrant and temporal quadrant within the 3 mm diameter of the center, and there was also a significant difference between the superior quadrant and inferior quadrant, and between the nasal quadrant and temporal quadrant within the 6 mm diameter of the center (p<0.01). CONCLUSIONS: Retinal thickness around the fovea as measured by OCT showed a decrease with age, although the fovea and the region within 1mm diameter of the center showed no statistical associations with age. |
| Key Words:
Age;Macular thickness;Optical Coherence Tomography |
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