Quantitative Analysis of Macular Thickness with OCT Map.

Lee, Dae Young; Yu, Seung Young; Kwak, Hyung Woo

Original Article

Journal of the Korean Ophthalmological Society 2004;45(9):1496-1502.
Published online September 1, 2004.

Quantitative Analysis of Macular Thickness with OCT Map.

Dae Young Lee, Seung Young Yu, Hyung Woo Kwak

Department of Ophthalmology, Kyung Hee University Hospital, Seoul, Korea. hwkwak@khmc.or.kr

광간섭단층촬영 지형도 검사를 이용한 정상인과 당뇨환자에서의 황반부 두께 분석

이대영 ( Dae Young Lee ) , 유승영 ( Seung Young Yu ) , 곽형우 ( Hyung Woo Kwak )

Abstract

PURPOSE
To analyse the macular thickness in normal and diabetic patient using OCT mapping protocol. METHODS: OCT using macular thickness map protocol was performed in 46 eyes of 25 healthy volunteers and 121 eyes of 85 diabetic patients with clinical diagnosis of no diabetic retinopathy (25 eyes), nonproliferative diabetic retinopathy (NPDR) without clinically significant macular edema (CSME; 35 eyes), proliferative diabetic retinopathy (PDR) without CSME (27 eyes), and diabetic retinopathy with CSME (34 eyes). RESULTS: The mean +/- standard deviation foveal thickness was 146 +/- 21 micrometer in normal eyes, 147 +/- 20 micrometer in diabetic eyes without retinopathy, 173 +/- 24 micrometer in NPDR without CSME, 174 +/- 27 micrometer in PDR without CSME, and 322 +/- 146 micrometer in diabetic retinopathy with CSME. There was significant difference in foveal and outer temporal retinal thickness between the normal eyes and the diabetic retinopathy without CSME group (p<0.01). Diabetic eyes with CSME had a statistically significant greater thickness in each of the areas compared with the other group and showed perifoveal focal macular edema in 5 eyes. CONCLUSIONS: OCT mapping protocol provide intuitive and objective information on focal diabetic macular edema.

Key Words: Diabetic retinopathy;Optical coherence tomography;Retinal thickness