Assessment of Retinal Ganglion Cell using Retinal Nerve Fiber Layer Photography in Age-related Macular Degeneration. |
Joo Youn Oh, Tae Young Chung, Dong Myung Kim, Hyeong Gon Yu |
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. hgonyu@snu.ac.kr 2Artificial Eye Laboratory, Seoul National University Hospital Clinical Research Institute, Seoul, Korea. |
맥락막신생혈관을 합병한 연령관련황반변성 환자에서 망막신경섬유층촬영을 이용한 신경절세포의 분석 |
오주연 ( Joo Youn Oh ) , 정태영 ( Tae Young Chung ) , 김동명 ( Dong Myung Kim ) , 유형곤 ( Hyeong Gon Yu ) |
|
|
Abstract |
PURPOSE To determine the loss of ganglion cell layer (GCL) neurons in patients with age-related macular degeneration (AMD) with choroidal neovascularization (CNV). METHODS: Retinal nerve fiber layer (RNFL) photography was taken in patients with AMD with CNV to assess the presence of RNFL defects in the papillomacular bundle area. Patients with other ocular disorders or a history of previous intraocular surgery or laser treatment were excluded from this study. RESULTS: Eighty-five eyes in 65 patients were included, of which only one (1.2%) showed papillomacular bundle defects in association with CNV. CONCLUSIONS: From this study, the majority of the patients with AMD with CNV had no papillomacular bundle defect, which demonstrates that considerable amount of GCL is maintained in AMD. |
Key Words:
Age-related macular degeneration;Age-related maculopathy;Choroidal neovascularization;Papillomacular bundle defect;RNFL defect |
|