Journal of the Korean Ophthalmological Society 2003;44(7):1559-1566.
Published online July 1, 2003.
A Relationship between Intraocular Pressure and Age and Body Mass Index in a Korean Population.
Jong Soo Lee, Cheul Min Kim, Hee Young Choi, Boo Sup Oum
Department of Ophthalmology, Pusan National University College of Medicine, Korea.
한국인의 정상 안압과 연령 및 비만지수와의 상관관계
이종수 ( Jong Soo Lee ) , 김철민 ( Cheul Min Kim ) , 최희영 ( Hee Young Choi ) , 엄부섭 ( Boo Sup Oum )
This study was carried out to evaluate the relationship between intraocular pressure (IOP) and age or obesity adjusted for systemic health parameters such as gender, mean blood pressure in a Korean population. METHODS: A total of 13212 healthy participants underwent automated multi-phasic test, including tonometry, automated perimetry, fundus photography, blood pressure, and body mass index (BMI). We used six age groups divided by decades ranging from 20 to 29 years to 70 to over 70 years old. The association between IOP and systemic health parameters was examined by means of cross-sectional analysis. RESULTS: The median age of participants was 47.6 years (range, 20 to 84 years), and 6684 (50.6%) of participants was males. The mean IOP of participants was 15.5 mmHg. The mean IOP, blood pressure, and BMI value was significantly higher in male than in female (P<0.05). The overall prevalence of ocular hypertension, defined as IOP > 22 mmHg without signs of glaucoma field or optic disc damages, was 6.1% in males and 2.5% in females. IOP was associated with mean blood pressure, gender, age, and BMI by multiple regression analysis (P<0.05). The relationship between IOP and age adjusted for gender, mean blood pressure, and BMI showed a significantly negative tendency in both genders (P<0.05). BMI had a significantly positive relation with IOP after controlling for age, gender, and mean blood pressure in male (P<0.05), but not in female. CONCLUSIONS: In this Korea population, after multiple adjustment, IOP was found to decrease with age in both gender and to increase with BMI in male.
Key Words: Age;Blood pressure;Body mass index (BMI);Cross-sectional analysis;Gender;Intraocular pressure (IOP)

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