Two Cases of Rhino-Orbitocerebral Mucormycosises that Manifested as Noninflammatory Oculomotor Nerve Palsy.

Cho, Ki Seok; Lee, Ju Yeoun

Case Report

Journal of the Korean Ophthalmological Society 2003;44(8):1919-1923.
Published online August 1, 2003.

Two Cases of Rhino-Orbitocerebral Mucormycosises that Manifested as Noninflammatory Oculomotor Nerve Palsy.

Department of Ophthalmology, Sacred Heart Hospital, Hallym University College of Medicine, Kyeonggi-do, Korea. ljy690725@hanmail.net

비염증성 동안 신경 마비로 발현된 비-안와-뇌 모균증 2예

조기석 ( Jo Gi Seog ) , 이주연 ( Lee Ju Yeon )

Abstract

PURPOSE
Rhino-orbitocerebral mucormycosis is the disease that cause orbital cellulitis, orbital apex syndrome, and orbital necrosis. We report two cases of mucormycosis that began with only noninflammatory oculomotor nerve palsy. METHODS: 74-year-old man and 53-year-old woman with DM visited our hospital for sudden ptosis, mydriasis, and paralytic strabismus. MRI scan and other neurological examinations were negative except mild sinusitis. Patients were diagnosed as complete third nerve palsy. RESULTS: A few days later, they developed orbital apex syndrome with exophthalmos and abrupt reduction of visual acuity. Emergency biopsy of sinusitis was done, and revealed mucormycosis. CONCLUSIONS: Sudden oculomotor nerve palsy in chronic debilitating patients with DM and sinusitis should be suspected as prodrome of rhino-orbito-cerebral mucormycosis.

Key Words: DM;Mucormycosis;Third Nerve palsy