Journal of the Korean Ophthalmological Society 2001;42(1):208-211.
Published online January 1, 2001.
Amniotic Membrane Transplantation for Late-Onset Filtering Bleb Leaks.
Tae Woo Kim, Jong Hyun Kim, Dong Myung Kim
Department of Ophthalmology, Seoul National University College of Medicine, Korea.
여과포누출에서 양막이식술의 효과
김태우(Tae Woo Kim),김동명(Dong Myung Kim),김종현(Jong Hyun Kim)
Abstract
Successful treatment of late-onset leakage of filtering bleb often requires conjunctival advancement or conjunctival graft with the risk of bleb failure. The authors performed amniotic membrane transplantation in two patients with Seidel-positive late-onset leakage of filtering bleb. In one patient, amniotic membrane transplantation(AMT)was performed twice. In the patient who underwent AMT twice, the bleb became Seidel-negative within 5 weeks of second AMT. However, it became Seidel-positive again within next 7 weeks. In the other patient, the bleb leak was partially resolved within 4 weeks, but became exuberant again within the next 4 weeks. In our experience, AMT had only a limited benefit in treating Seidel-positive bleb leaks. However, its initial success suggests that further studies are necessary to better understand the role of amniotic membrane in bleb leak and to develop a potential therapeutic modality for treating late-onset filtering bleb leak.
Key Words: Amniotic membrane;Late-onset filtering bleb leak


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