The Comparison of Tear-Specific Prealbumin in Diabetc Patients with Normal Subjects.

Cho, J K; Song, B R; Yoo, J H; Chang, J S; Byon, D S

Original Article

Journal of the Korean Ophthalmological Society 1999;40(11):2955-2960.
Published online November 1, 1999.

The Comparison of Tear-Specific Prealbumin in Diabetc Patients with Normal Subjects.

J K Cho, B R Song, J H Yoo, J S Chang, D S Byon

¹Department of Ophthalmology, College of Medicine, Inha University.
²Department of Biochemistry, College of Medicine, Inha University.

정상인과 당뇨환자에서 Tear - Specific Prealbumin 의 비교분석

유중하(Joong Ha Yoo),조제군(Jae Kun Cho),송백란(Beak Ran Song),장정순(Jung Sun Chang),변도석(Do Seok Byon)

Abstract

Human tear proteins serve many roles to maintain the health and intergrity of the preocular tear film and ocular surface environment. The proportion of tear proteins can be changed markedly in various ocular diseases. We studied concentration of TSP[tear-specific prealbumin] in normal subjects and diabetic patients. These studies was also done in group that had less than 10 years of diabetes and group that had more than 10 years of diabetes. We evaluated the association between the diabetes and the proportion of tear proteins and these evaluation was also done between the duration of diabetes and TSP. We analysed concentration of TSP from 30 diabetic patients. 30 normal subjects were used as age-matched controls. As a result, the concentration of TSP in diabetic group is lower than that in normal group and the concentration of TSP in diabetic group that had more than 10 years of diabetes is lower than that in diabetic group that had less than 10 years of diabetes.

Key Words: Diabetic patients;Tear-specific prealbumin;Tear proteins